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An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]

A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
Deer Antler Velvet Pro has made an impact on the way elite athletes perform by providing them with the extra boost in strength and power they need to achieve their optimal performance. With 750mg of deer antler velvet powder in every serving, you can be sure that you’ll get an increase in your energy levels, lengthen your endurance abilities, and improve your sexual vitality. Read More…
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The chairman of the Olympic Committee mandated all athletes use their patented deer antler extract to increase recovery, growth and performance. Don't you remember the Soviet who dominated Rocky? And to those who know their history, the Soviets did actually dominated Olympic sports, especially weightlifting, from the early 70's to the late 80's. Could this have been a secret confidential edge?
In another randomized, double blind, placebo controlled experiment (Broeder, 2004), 38 males, all of whom were experienced weightlifters, entered a 10 week strength training program. Those who took deer antler velvet experienced an increase in peak torque and average power relative to the placebo group. They also experienced unexpected improvements in aerobic performance.
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“Nutronics Labs Deer Antler Spray is an incredible product. After just a few days of using it, I noticed a significant decrease in the chronic knee arthritis pain I’ve suffered from for many, many years due to dancing and sports injuries. As an added bonus, my ENTIRE body suddenly felt lighter, and generally pain free…it wasn’t until taking the product that I realized most of my joints had been stiff and achey. I had been living in pain for years without even realizing it, having become accustomed to being constantly uncomfortable and sore. I was able to work out harder, recover faster, and noticed significantly increased flexibility and overall mobility. I noticed substantial improvement in muscle tone.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed.[26] The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.[27]
“I've been taking deer antler since 2012 so I've been taking it for years and I definitely believe in it. And for recovery after hard, intense workouts, deer antler is a must. Go to AntlerFarms.com, definitely get the [deer antler velvet extract tablets] and the [deer antler velvet capsules]. Take those two in combination and you will feel great.”*
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
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