Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.
Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves, although testosterone may be the primary growth factor. Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.
"Here's my advice to you. Find a product that contains the right kind of high quality grass fed whey protein isolate and is sweetened with the right kind of sweetener. I did want to give a shout out to Antler Farms® who has a nice, high quality New Zealand Whey Protein Isolate. They've gone the extra mile in a lot of different directions. I like to give shout outs to companies that I think deserve it and actually care about our health."*
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization. In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to. (That’s not a value judgment, just the facts.)
Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes. In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars. In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." 
Using deer antler velvet benefits sexual functions and libido by helping to increase gonadotropin hormones which include luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Luteinizing hormone (LH) and follicle-stimulating hormone are hormones that stimulate the sex glands. The stimulation of the sex glands is pivotal for sexual reproduction. Without the presence of the gonadotropin hormones, the sexual organs will fail at their purpose and the individual will be considered infertile. As the deer antler velvet promotes an increase in LH, the LH causes the testes to produce more testosterone.
Published research has shown that IGF-1 can produce similar results to growth hormone. The catch? If you do the math from the study, a 150-pound man (that’s a pretty small guy, so a bigger man would need more) would have to take more than 25 million nanograms just to experience the growth hormone-like effects of more muscle, less fat, and faster recovery.
Deer antlers have been closely linked to IGF-1, which is another term for insulin. This has been well received in eastern medicine as an anti-aging and bodybuilding product. Because it’s also a known natural growth hormone, it’s said to aid in muscle development by enhancing strength and improving recovery time. This is what attracts bodybuilders to this product.
Moose, elk and deer produce new antlers yearly (primarily males, except in caribou/reindeer). In New Zealand, deer are subject to local anesthesia and restrained during antler removal, and the procedure is supervised by licensed veterinarians. Typically, the antler is cut off near the base after it is about two-thirds of its potential full size, between 55 and 65 days of growth, before any significant calcification occurs. The procedure is generally done around June in the Northern Hemisphere and December in the Southern Hemisphere.
World harvest extends far and wide. The farming of deer species for their velvet antler has been occurring for a long time in China and Russia. The Asian industry raises a predominant amount of sika, aka. spotted deer, on private and communal farms where they are well cared for by private owners. Quality of a this profound botanical is of utmost importance. Farms in Asia it is also both industry and government regulated for quality, safety, and the welfare of the animals.