Most of the world's supply of velvet antler comes from Sika deer, red deer and elk or wapiti, including a large deer ranching industry in New Zealand. New Zealand is the world’s largest producer of velvet, producing 450-500 tons of red deer velvet antler annually. China produces 400 tons of predominantly Sika deer velvet antler annually. Russia produces 80 tons annually. United States and Canada each produce 20 tons annually.
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In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.
One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed. The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.
On January 30, 2013, Vijay Singh professional PGA Tour golfer was caught unaware and openly admitted to the personal use of deer antler spray which contained a banned substance at the time. A week later the World Anti-Doping Agency (WADA) lifted the ban on deer antler spray, but with urgency, "Deer Antler Velvet Spray may contain IGF-1 and WADA recommends therefore that athletes be extremely vigilant with this supplement because it could lead to a positive test."  The consensus opinion of leading endocrinologists concerning any purported claims and benefits "is simply that there is far too little of the substance in even the purest forms of the spray to make any difference,"  and "there is no medically valid way to deliver IGF-1 orally or in a spray." 
The IGF-1 in deer antler velvet can help increase the body's natural healing by affecting cell repair and growth. When an injury or surgery occurs that leaves a wound on the body, the wound is healed naturally by the cells which line the wound. Those cells multiply and rejoin over time. Using deer antler velvet can help promote faster cell repair and growth so that the wound can heal at a faster rate which means less time being injured or sore.
In Russia, Korea and China, deer antler velvet is widely used by athletes to enhance performance. In the United States, more and more athletes are looking to deer antler velvet as a training aid, a promoter of recovery after physical activity and injury, and possibly an injury preventative. Deer velvet could improve athletic performance in many ways, for example by assisting strength and endurance, by supporting the oxygen-carrying capacity of the blood, by facilitating minor tissue damage, and by boosting the immune system.
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“I've been taking deer antler since 2012 so I've been taking it for years and I definitely believe in it. And for recovery after hard, intense workouts, deer antler is a must. Go to AntlerFarms.com, definitely get the [deer antler velvet extract tablets] and the [deer antler velvet capsules]. Take those two in combination and you will feel great.”*
If you have any existing medical condition that requires taking medication, always consult your physician before taking any new products. Discuss if deer antler spray will be safe for you to use if you have a history of serious hormonal problems, heart disease, liver or kidney disease, or any other serious condition. It’s also not wise to stop taking any medications you’ve been taking or to end physical therapy sessions/exercises because you’ve started taking deer antler spray. Always follow up with your doctor or therapist if you have questions about changing your recovery plan regarding an injury or illness.
L-Arginine: An amino acid usually found in red meats that is important for the body’s ability to manufacture proteins. L-Arginine has been used to treat conditions like high blood pressure, congestive heart failure, blocked arteries, and erectile dysfunction. L-Arginine is safe for most people, however it should not be taken by women that are pregnant or breastfeeding.