For those of you in your teens and 20’s, if you take this type of supplementation your body will begin to stop producing this naturally; and that right there is NOT a good thing. If you really believe you are getting some benefit from using this supplement than you will need to take more and more as your body stops making it completely (at an early age), and will most very likely have complications later, if not sooner, due to having to increase your dose. Therefore when it is found, and it is known that IGF-1, the active ingredient of why Deer Antler Velvet is used, can cause cancer, especially prostate cancer and the enlargement of other vital organs in the body, not muscles.
Deer antler velvet can help slow the aging process and possibly even increase longevity due to the IGF-1 present in deer antler velvet. Aging occurs because our DNA becomes damaged throughout our lives and the damages accumulate over time. The damaged nuclear DNA can either directly cause the aging process by increasing cell dysfunction or it can indirectly cause the aging process by increasing programmed cell death (apoptosis) or increasing the number of cells which are unable to divide any further (cell senescence).
Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits. It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels. Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer. Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.
One of the leading companies in the world that manufacturers deer antler spray is called Nutronics Labs. According to information posted on their website, they have been making deer antler supplements for two decades. They state that their deer antler products range in concentration/strength from about 25,000ng (nanograms)–200,000ng of IGF-1. According to studies done by Nutronics Labs, deer antler powders appear to be less concentrated with IGF-1. They also may be poorly absorbed compared to deer antler extract.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.