Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes.[18] In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars.[19][20] In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." [21]

Deer antler products contain mostly amino acids (that form proteins) along with growth factors, which are poly-peptide bonded amino acid chains. (4) The most abundant growth factor is IGF-1. However, it isn’t a factor found in these products. Depending on the specific brand, deer antler spray/powder/capsules may contain amino acids and growth factors including: (5)
The harvesting of deer antler velvet can be a painful process, as the velvet tissue contains an abundance of nerves and bleeds profusely if cut or removed. Dr. Low Dog says she has no problem with harvesting velvet from deer killed for food, but is concerned that shortcuts will be taken should demand for the supplements continue to grow. She notes that the United Kingdom has banned the removal of deer antler velvet under its welfare-of-livestock regulations, unless the antlers have been damaged or most of the velvet has been shed.
The product smells like lemon-scented cleaner and bears a resemblance to murky pond water. I hesitantly tried the stuff and found it surprisingly palatable, with a lemon taste, but not too sour and slightly sweet. The directions say to take 14 drops under the tongue, three times a day, but I stopped after one dose — so I probably don't have a good chance of reaping the benefits, if there are any.

When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1. 

I know of no scientific evidence to support any of the marketing claims made for these supplements. I discussed your question with Tieraona Low Dog, M.D., an internationally recognized expert in the fields of integrative medicine, dietary supplements and women’s health, and an authority on botanical medicine. She explains that IGF-1 in the velvet promotes rapid growth of the antler. Dr. Low Dog notes that the two studies examining the effects of deer antler velvet supplements taken by athletes have yielded conflicting results. One showed some improvements in endurance and knee strength in weightlifters, but the other found no differences in rowers after 10 weeks of supplementation.
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There must be a reason to is use and a booming world industry that garners the attention of several researchers and scientist in many countries. Modern understanding has greatly advanced our knowledge of velvet antler. We know by its composition and the knowledge of the structure and function of the plenitude of constituents which work together, like a symphony, to create an efficacious supplement that yields a multitude of benefits.
L-Arginine: An amino acid usually found in red meats that is important for the body’s ability to manufacture proteins. L-Arginine has been used to treat conditions like high blood pressure, congestive heart failure, blocked arteries, and erectile dysfunction. L-Arginine is safe for most people, however it should not be taken by women that are pregnant or breastfeeding.
To be clear, some doctors and researchers have stated that they feel deer antler spray is unlikely to cause any significant benefits. This is because it only provides very small amounts of IGF-1, some of which may not even be fully absorbed. However, studies do show that higher doses, or using very high-quality supplements, may contribute to some improvements in performance, body composition, etc. IGF-1 itself has been studied extensively. It can certainly change the way the body looks and operates. Whether or not the role of IGF-1 in the body will translate into any real benefits when obtained from deer antler products will depend on the specific person and dosage used.

A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
Immortal Antler Velvet Gold is the Mercedes of antler velvet extracts. It is the only all-natural 43:1 extract that contains a powerful blend of growth factors in a naturally occurring matrix. These naturally occurring growth factors are involved in every cellular function in the human body, from metabolism to immune response. Immortal Antler Velvet Gold is the only all-natural proprietary matrix to deliver up to 100 mcg’s of IGF-1 per bottle, in addition to the full growth factor matrix. Delivering a full range of growth factors at an alarming 43:1 ratio means there is no stronger formula on the market today. This ratio means it requires 43 lbs of velvet antler tips to create 1 lb of this complete formula. It is extracted in organic grape alcohol and bottled in miron violet glass for maximum absorption and effectiveness.

Deer Antler Velvet Spray is an extract that’s taken directly from the material that grows on the outside of the antlers of deer, elk, moose and caribou. Their website suggests its use for anyone that is looking to counter the effects of light exercise, mild muscular strain and exertion, and some arthritic conditions. In addition to providing joint support, Deer Antler Velvet Spray is said to balance hormone levels, build muscle, boost sexual performance, and improve immune function.
Deer antler spray products are not cheap. Expect that buying a high-quality product will set you back about $60–$100 per bottle. When taken as directed, each bottle should last you about one month. You don’t need to refrigerate the spray. However, keep it away from very hot temperatures to preserve the chemical composition of the product. Manufacturers claim that you can start experiencing benefits within 3–4 days. However, results definitely differ from one person to the next.
New Zealand research reports that although the mechanism is unknown, deer antler velvet shows strong anti-inflammatory effects. Recent clinical tests suggest oral ingestion of glycosaminoglycan-peptide complex, or components such as chondroitin sulfate and glucosamine sulfate — both found in deer antler velvet — may help stimulate cartilage repair.
The product smells like lemon-scented cleaner and bears a resemblance to murky pond water. I hesitantly tried the stuff and found it surprisingly palatable, with a lemon taste, but not too sour and slightly sweet. The directions say to take 14 drops under the tongue, three times a day, but I stopped after one dose — so I probably don't have a good chance of reaping the benefits, if there are any.
Shake bottle before each use. Then take 12 drops under the tongue twice a day. Hold the liquid under your tongue for 20 seconds before swallowing. This allows the formula to penetrate through your endocrine glands. Then the active molecules are released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability!
Deer antler velvet may help to increase macrophage activity. Macrophages are a type of white blood cell (immunity cell) that digests cellular debris, foreign substances, cancer cells, and other microorganisms. Macrophages help to stimulate defense mechanisms in the body by recruiting immune cells such as lymphocytes. With this increased number of white blood cells, your immunity system becomes strengthened and will have a better chance at fighting off a sickness or infection.

Generally researchers agree that deer antler velvet protects, strengthens and restores the body's functions that are out of balance. In other words, it can act as an adaptogen on the human body, helping where it is needed. Studies suggest that deer antler velvet may have beneficial effects related to: increases in muscular development, strength and endurance; improved recovery; prevention and reduction of inflammation; improvement of sexual health; reduction in blood pressure; improvement in bone and joint health; stimulation of the immune system; and more.

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