However, calcium and phosphorus levels (which are important for bone growth) did not differ among groups. Overall, the researchers concluded that “our results seem to support a role for dietary supplementation of EVA on growth and bone development in this model.” (9) However, it’s important to point out that this is a very high dose. It’s significantly above what most would take in supplement form.
I know of no scientific evidence to support any of the marketing claims made for these supplements. I discussed your question with Tieraona Low Dog, M.D., an internationally recognized expert in the fields of integrative medicine, dietary supplements and women’s health, and an authority on botanical medicine. She explains that IGF-1 in the velvet promotes rapid growth of the antler. Dr. Low Dog notes that the two studies examining the effects of deer antler velvet supplements taken by athletes have yielded conflicting results. One showed some improvements in endurance and knee strength in weightlifters, but the other found no differences in rowers after 10 weeks of supplementation.
Published research has shown that IGF-1 can produce similar results to growth hormone. The catch? If you do the math from the study, a 150-pound man (that’s a pretty small guy, so a bigger man would need more) would have to take more than 25 million nanograms just to experience the growth hormone-like effects of more muscle, less fat, and faster recovery.

I recently ordered IGF-1 Plus Maximum in order to gain results from my physical therapy workouts. Since using this product, I am not only able to do harder workouts, but I also have increased muscle mass. Besides these benefits I have experienced improvement in my wound healing! Areas that repeatedly break down are showing increased healing like never before. My hands, which are severely scarred, have more flexibility. I look forward to the many benefits that may come from using IGF-1. Thank you Rick Lentini!
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims.[12] The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)][36] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA.[12][14][15][16][17] As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."

Data is limited. Two studies (n=40 and 168) investigating the efficacy of elk velvet antler supplementation on rheumatoid arthritis found no effect, while a study conducted in people with osteoarthritis (n=53) reported symptomatic relief among participants. The small sample sizes may result in the trials being underpowered to detect effects.25, 28, 29

Adaptogen: Adaptogens are natural metabolic regulators that increase a person’s ability to adapt to environmental factors-like pollution, smoke, stress, toxins etc. and to avoid damage from those factors. In other words, adaptogens literally help your body “adapt” to the environment without any side effects. If you’re living in the real world, with external or internal stressors, adaptogens help your body change in order to cope with the stressors.
I have not felt much differently since I started taking the deer antler however I did notice that when I do the arm bike I can do it faster and longer without weakness. Now you would say so big deal. For me that is a huge difference that I am tracking. I NEVER was good on the arm bike even when I was in shape it felt more labored. I am horribly out of shape for me and yet I can do this with comfortable effort. I also have taken the REM product Anna Nova health offers. Now this is where I DO notice a difference again but much more that the daily effect. My sleep has regulated to where most nights I have been able to sleep at least 5-6hrs straight. I have done that in the past. What I notice is that my body actually FEELS rested like i went into a deeper sleep. I have tried everything to sleep. Some things that are suppose to help actually work the opposite. Most all drugs have horrible effects on me and I NEVER wake up rested. I wake up foggy doppy and irritable-if I sleep. I have to say something about this works. Maybe it effects my body chemistry in manner it needs. I don’t know but its not because I WANT it to work. I have taken all this stuff tried all this stuff expecting failure. I have not slept well my whole life. Since the head injury even if I do sleep I’m not rested nor do I feel that my body relaxes. Since I have taken this after two weeks I noticed a big difference. 5hrs for most people is horrible- for me its good 6 is great and my ideal sleep. I am staying on it for another couple months to see if I feel or notice any other differences. As far as helping “heal” my body WIM hof cold exposure works the best for my brain so far. Brain injury/neck injury people are different from those without. We have dysfunctional nerves neurotransmitters and path waves that cause things to happen that we need to find other ways to fix. Drs just don’t listen and pay attention to people who are in tune with their bodies. Its too bad cause they could learn a lot from us.
Studies have found that deer antlers themselves contain a highly concentrated amount of essential trace minerals, fatty acids, amino acids and growth factors that can all support the immune system. This includes the gastrointestinal tract, where the majority of the immune system is found. Antlers contain minerals such as: calcium, phosphorus, magnesium, iron, potassium and sodium in addition to numerous minor components.
I took red mountain deer velvet and it really messed my stomach up. I now have cramps and bloating all the time plus it feels like my stomach shrank…I can’t eat like I used to. It was a big mistake to take that stuff. Do you know of any way I can get my stomach back to normal??? Can you recommend someone who knows a lot about deer velvet?? I have been suffering terribly since I took that junk…it’s been about 2 years now!!!! My stomach has never been the same since I took that poison!!

All groups experienced a significant improvement in strength. But the deer antler powder group showed the greatest increase in isokinetic knee extensor strength and endurance. However, it’s possible that this was due to exercise program rather than using the deer antler powder. None of the men in any group showed evidence of endocrine, red cell mass or VO2max changes. Therefore, researchers concluded that the “findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet.” (12) On the other hand, this was a small study, with only 12-13 men in each group. This means that further testing is needed to confirm the validity of the results.
In September, 2013, the headquarters of S.W.A.T.S. was raided and ordered to be shut down by Alabama's attorney general citing "numerous serious and willful violations of Alabama’s deceptive trade practices act".[30][31] Among the violations were "claims that the company made about a number of products that were unsupported by scientific research. Some of these products were marketed as 'dietary supplements.'" [32] The assistant Alabama attorney general "says that Deer Antler Spray is dangerous and its sellers are law-breakers." [33]
In a study on diabetic mice given topical wounds (scalpel and scissors to create a cricle; diabetes tends to reduce wound healing rates[34] and thus diabetic rats are a good research model for wound closure rates) where either a control cream or one containing 400mcg Velvet Antler (Elk; water soluble extract) noted that there was less angiogenesis and a trend towards less inflammation assocaited with Velvet Antler cream while on day 7 wounds treated with the Antler cream were significantly smaller than control.[35] One 3.2kDa protein has been noted to possess wound healing properties, which are dose-dependent and have been noted to improve wound healing induced by burns at 0.05-0.1% of solution[36] and in vitro at 10-40mcg/mL.[37]

Deer velvet might have an effect due to the hormones it may contain, including testosterone, androstenedione, and dehydroepiandrosterone. Research in rats, using elk velvet antler, suggested the substance may have an androgen-like effect. The antlers are ground into powder, which people take by mouth. Dosage varies by brand, but a recent study used 215 mg per day. Some distributers, though, recommend dosages ranging from 250 mg to as high as 3000 mg (3 g) per day. So talk with your doctor before you start using deer velvet.
Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.
Now, you’ll probably read a lot about the power of IGF-1 in many reports about Ray Lewis. And while it’s true that IGF-1 is illegal in man-made form, let’s not mistake illegal products (because they are synthetic) with guaranteed amazing results. IGF-1 can have a significant impact on your body, but it’s not that easy to get the levels you need from deer antler. In fact, given what’s in a typical bottle, it is damn near impossible.
In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 
The company has found that powders have only about a 15–20 percent absorption rate of IGF-1. This is due to how the digestive system breaks down the powder. Nutronics states that their “proprietary sublingual spray delivery system” is superior to many competitors because it offers “enhanced bioavailability” of IGF-1. They also point out that “it is not the milligrams of Deer Antler Velvet in the product, it’s the content of IGF-1 and other Growth Factors in Deer Antler Velvet, that makes the difference.”(6)
“I've been taking deer antler since 2012 so I've been taking it for years and I definitely believe in it. And for recovery after hard, intense workouts, deer antler is a must. Go to AntlerFarms.com, definitely get the [deer antler velvet extract tablets] and the [deer antler velvet capsules]. Take those two in combination and you will feel great.”*

“As a Pro MMA, fighter I was always looking to find a product to keep me in the gym training as hard I can. I raise 3 children and they keep me on my toes all day long, up until its training time. While hitting the gym after running through play grounds and countless tea parties with my daughter throughout the day, it was hard to keep my energy up enough to get through my training without wanting to quit and go home for the day. Now after using your Igf-1 for a while now, I see way better results in my training. I am able to hang with my children all day, able to sit through all the tea parties, and chase after kiddos as long as they can go. My training is 100% better then it was. I don’t stop training until I just want to. My energy, stamina, focus, mentality and over all performance in anything I do, has increased so much its hard to believe. I am able to recover faster and feel stronger each time I do. If you're not using Nutronics products you're missing out! By far worth any amount of money in the world when it comes to this life changing opportunity to better yourself in anything you do, whether you’re an athlete or just looking for an improvement.”
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
Deer antler velvet is the tissue that covers the bone and cartilage that develop into deer (and elk) antlers. It has been harvested for centuries and used traditionally to increase strength, boost the immune system, and counter the effects of stress. Now it’s promoted to improve athletic performance; raise testosterone levels to increase sex drive, fertility and erectile function in men; as well as to reduce the signs of aging and treat problems ranging from high cholesterol, high blood pressure, asthma and osteoporosis to migraine headaches, indigestion, and many more.
Deer antler spray — a supplement commonly used in the fitness and sports industries that has a long history of use in Eastern medicine — is pretty much as strange as it sounds. Derived from the tissue found inside deer antlers, it’s reported to work by providing IGF-1 (insulin-like growth factor), a natural growth hormone found inside the human body that has potential to increase muscle mass and support recovery from injuries.
According to an article in Sports Illustrated, Lewis spoke by telephone after his injury with Mitch Ross, co-owner of the supplement company S.W.A.T.S. (Sports with Alternatives to Steroids) to ask about treatments that could speed his recovery. Sports Illustrated reported that among Ross’ recommendations were deer antler pills to “rebuild your brain via your small intestines.” In addition to recommending the pills, Ross reportedly also told Lewis to spray deer antler extract under his tongue. Lewis has denied following this advice, and Ravens’ management has said that the star player has never flunked a drug test.
Bottom line: Rogol says it’s “extremely unlikely” that deer antler in any form could offer athletes a boost. “Deer antlers do contain growth factors,” he explains. But it’s a huge leap of faith to talk about an extract doing anything beneficial for human beings, whether it’s slowing aging, developing muscle, or repairing tendons, he adds. Opinions like Rogol’s are one reason the FDA and anti-doping agencies haven’t yet taken steps to ban deer antler products that contain IGF-1.
The first question to ask, is why? Why are you considering this supplement? A supplement is not intended to fix a crappy diet or poor exercise program. A supplement is intended to be just that, a supplement to your existing good diet/good exercise program. And if you’re eating a well-rounded diet, then there’s really no need for supplementation at all.
Performance - Borrowing the scientific research, its mandatory use by the Soviets has shown increased blood circulatory benefits, liver protective attributes and nerve strengthening effects of the aqueous alcohol extract.* This means it increases nervous innervation, easily known as the contractile capacity of muscle groups.* This leads to short burst style athletic performance increases found in weightlifting, bodybuilding, and similar sports.*

Although previously found on the World Anti-Doping Agency's list of banned substances, Deer Antler Spray was removed in 2013 when it was deemed completely safe and legal to consume prior to athletic activity. Deer Antler Spray has been known to speed up the rehabilitation process of injuries, especially injuries effecting cartilage. It has also been known to boost endurance and strength, increase muscle mass, decrease fat, and raise one's testosterone levels, thus increasing libido. The use of Deer Antler Velvet Spray has been linked to several athletes, including football star Ray Lewis, who is rumored to have used it following an injury to his tricep in 2013.


Fat Metabolism* -Besides containing a plethora of nutrition, such as peptides, growth factors and important minerals, which may help to prevent cravings, deer antler velvet also contains ursolic acid, which may be beneficial for increasing fat metabolism, we can, with a little effort and motivational boost, achieve a leaner and firmer physique.* Additionally, research in other fields suggests that it may be responsible for a smaller waist.*
Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Many conditions lead to joint pain from aging to an untreated sports injury. A quality joint product may help repair existing tissue damage and also promote stronger joints, less susceptible to future degeneration.

Other studies reported an increase in heart strength and volume of blood pumped, while cardiac output, heart rate, mean arterial pressure, pulse pressure, central venous pressure and other parameters remained unchanged. Researchers suggest that the polysaccharides in antler may reduce the blood’s tendency to clot, improving circulation, decreasing stroke risk and boosting general cardiovascular health. Researchers theorize that the deer antler velvet may improve blood supply to muscles or act as an anti-inflammatory, allowing athletes to recover faster from training sessions.
The FDA considers deer antler spray (or deer antler velvet) to be a dietary supplement. This means it doesn’t need to be extensively studied and regulated like medications. For this reason, it can be hard to tell what the actual concentration of active ingredients or IGF-1 is in various supplements. Plus products can differ quite a bit from one brand to another in terms of their purity and effectiveness.
“As a Pro MMA, fighter I was always looking to find a product to keep me in the gym training as hard I can. I raise 3 children and they keep me on my toes all day long, up until its training time. While hitting the gym after running through play grounds and countless tea parties with my daughter throughout the day, it was hard to keep my energy up enough to get through my training without wanting to quit and go home for the day. Now after using your Igf-1 for a while now, I see way better results in my training. I am able to hang with my children all day, able to sit through all the tea parties, and chase after kiddos as long as they can go. My training is 100% better then it was. I don’t stop training until I just want to. My energy, stamina, focus, mentality and over all performance in anything I do, has increased so much its hard to believe. I am able to recover faster and feel stronger each time I do. If you're not using Nutronics products you're missing out! By far worth any amount of money in the world when it comes to this life changing opportunity to better yourself in anything you do, whether you’re an athlete or just looking for an improvement.”
In a double blind study (Edelman, 2000), 54 patients with arthritis in the knee were given deer antler velvet or a placebo and assessed at 1, 3 and 6 months. Patients treated with deer antler velvet showed improvement in pain and physical global assessment at 3 and 6 months. No significant improvement was observed for the placebo group for any of the parameters examined.
Joint Health & Injury Recovery* - Due to certain constituents recognized by the government one will benefit by better joint health, plus the content of proteins similar to our own bodily structures are plentiful within deer antler supplements, such as type II collagen.* Another involved and interesting cellular activator known as hyaluronic acid has many additional benefits for repair and regeneration.
Assuming that deer antler velvet is the next biggest thing in muscle building and athletics isn’t just a massive leap of faith, it’s something that can’t be supported by science in any way, shape, or form. So why is it illegal? Because it’s still a synthetic, man-made growth hormone precursor. Those are illegal, according to most professional sports.
Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor).
Suggested use: Take one tablet 20-30 minutes prior to your two main meals of the day with 8oz. glass of water. You may also use Nutronics Labs Weight Loss Plus in conjunction with any of our IGF-1 liposome spray products for optimal results. Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication.
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