Although previously found on the World Anti-Doping Agency's list of banned substances, Deer Antler Spray was removed in 2013 when it was deemed completely safe and legal to consume prior to athletic activity. Deer Antler Spray has been known to speed up the rehabilitation process of injuries, especially injuries effecting cartilage. It has also been known to boost endurance and strength, increase muscle mass, decrease fat, and raise one's testosterone levels, thus increasing libido. The use of Deer Antler Velvet Spray has been linked to several athletes, including football star Ray Lewis, who is rumored to have used it following an injury to his tricep in 2013.
In rats undergoing left coronary artery ligation, those with heart failure were given either Velvet Antler (Deer) or Captopril as active control for 4 weeks with a third group given water. No significant changes in cardiac structure was noted with either Velvet Antlers or Captopril (with the heart tissue being enlarged after heart failure) although left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) appeared to be improved in both treatment groups to approximately the same degree and the increase in serum Brain Natiuretic Peptide (BNP) that occurred with heart failure was attenuated the same degree in both interventions.
IGF-1 can help slow this aging process down by increasing the telomere length of our DNA. Telomeres are a protective "cap" at the end of each strand of our DNA which prevents the DNA from becoming damaged. DNA becomes damaged as the telomeres grow shorter with age. As more DNA strands become damaged, cells in our bodies can no longer function properly which results in many medical conditions, diseases, and even death. This is how IGF-1 can help longevity. It does this by promoting healthy DNA strands to keep our cellular functions optimal.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.