"I am 60 years old and had polio when I was six months old. Throughout my childhood I had 7 orthopedic surgeries to correct the damage leftover by polio to my left hip, leg and foot. I am battle scarred and a Post Polio Syndrome Survivor. I cannot praise your product enough! Its difficult for me to walk. I normally use a battery powered scooter in malls and airports. The least amount of physical exertion walking and standing creates days of agony afterwards. This past Saturday I walked the mall, went for a movie and dinner. I was active all day and well into the night without tiring. I kept waiting for the intense painful spasms and muscle contractions from my polio atrophied muscles in the left leg and also my hips. Usually late at night is when the pain and spasms are the most intense. But guess what? I am not hurting anywhere near the level I use too. I am not fatigued. I used Antler Farm's Deer Antler Velvet a couple of years ago when traveling to Machu Picchu, Peru. I am still amazed I climbed the ancient Inca Trail unaided with just my cane. Antler Farm's Deer Antler Velvet has improved my quality of life significantly."*
Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves, although testosterone may be the primary growth factor. Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.
While Lentini admits sales have picked up, he says he's been hurt by the perception in the recent baseball letter, which told players that deer antler velvet could be contaminated with methyltestosterone, a banned steroid. The connection is based on the fact that David Vobora tested positive for the steroid after using antler spray. He won a $5.4 million judgment against the company that made the spray.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.