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Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves, although testosterone may be the primary growth factor. Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.
"I was diagnosed with Muscular Dystrophy at the age of 3. For those of you who do not know Muscular Dystrophy is a disease that essentially means muscles with bad nutrition. My results with this product have been phenomenal. I've definitely noticed an increase in energy, definitely strength. I went from 12 reps to 43 reps in just five weeks. There is something special about this product."*
Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
Even more intriguing is how the stags manage to regrow their antlers. Scientists have found stem cells at the bases of antlers’essentially ‘blank’ cells that can develop into many different types of cell, such as a skin cell or a cartilage cell. If they could find out what triggers the stem cells and controls their development into antlers, the knowledge could be applied to the regeneration of human limbs and organs. Scientists know that the shedding is initiated by a fall in the hormone testosterone, a change linked to an increase in day length, and they think oestrogen may be a key cellular regulator. However, much more research on a molecular level is required to unravel what is clearly an intricate process.
Bottom line: Rogol says it’s “extremely unlikely” that deer antler in any form could offer athletes a boost. “Deer antlers do contain growth factors,” he explains. But it’s a huge leap of faith to talk about an extract doing anything beneficial for human beings, whether it’s slowing aging, developing muscle, or repairing tendons, he adds. Opinions like Rogol’s are one reason the FDA and anti-doping agencies haven’t yet taken steps to ban deer antler products that contain IGF-1.
In Chinese medicine, deer velvet has been used to treat impotence, female disorders, urinary problems, skin ailments, and knee weakness. It is also employed as a tonic in children with learning disabilities or insufficient growth.16 Koreans use antler velvet to treat anemia and impotence and to stimulate the immune system, treat impotence, improve heart function, muscle tone, lung efficiency, and nerve function.17
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization. In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to. (That’s not a value judgment, just the facts.)
"I have been real happy with the results. My lifting has definitely increased alot. I've gotten alot stronger. My endurance is amazing too. It's kind of had a domino effect on my workouts and my health overall. I've added almost 10 lbs. of muscle, which has been great. If you are looking for a good product to take, I highly recommend the one I came across and the one I have been using, Antler Farms®."*
Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims. The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA. As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."
In herbal combinations, deer velvet is used to improve athletic performance; to improve eyesight and hearing; to reduce stress; and to treat arthritis, osteoporosis, “tired blood” (anemia), women’s reproductive disorders including premenstrual syndrome (PMS), ED, and skin conditions. Herbal combinations including deer velvet are also used to increase blood circulation to the brain and to delay or reduce signs of aging such as tissue, bone, and muscle degeneration, and declining mental skills.
Fat Metabolism* -Besides containing a plethora of nutrition, such as peptides, growth factors and important minerals, which may help to prevent cravings, deer antler velvet also contains ursolic acid, which may be beneficial for increasing fat metabolism, we can, with a little effort and motivational boost, achieve a leaner and firmer physique.* Additionally, research in other fields suggests that it may be responsible for a smaller waist.*
Tribulus: An extract taken from the Mediterranean puncture vine that some cultures believe to have medicinal values. There is little clinical data surrounding the bio-physical effects of tribulus, however some people take it to enhance athletic performance, sexual ability, and improve circulation. Not much is known about the long-term consequences of tribulus consumption, however there are some indications that it may potentially lead to prostate issues in some men.
I never take a product without doing my research, because it is always good to know what you're putting in your body. I looked at several sources including scholarly journals about many of the ingredients in Deer Antler IGF-1. It is a great product, and has been proven to work without ANY side effects. This product has definitely been helping with my lean muscle gains during my improvement season. It gives me energy before a workout, and it gives me some great vascularity while I'm lifting!
To be clear, some doctors and researchers have stated that they feel deer antler spray is unlikely to cause any significant benefits. This is because it only provides very small amounts of IGF-1, some of which may not even be fully absorbed. However, studies do show that higher doses, or using very high-quality supplements, may contribute to some improvements in performance, body composition, etc. IGF-1 itself has been studied extensively. It can certainly change the way the body looks and operates. Whether or not the role of IGF-1 in the body will translate into any real benefits when obtained from deer antler products will depend on the specific person and dosage used.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.
“I've been taking deer antler since 2012 so I've been taking it for years and I definitely believe in it. And for recovery after hard, intense workouts, deer antler is a must. Go to AntlerFarms.com, definitely get the [deer antler velvet extract tablets] and the [deer antler velvet capsules]. Take those two in combination and you will feel great.”*