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According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.

In an experiment (Gerard, 2004) conducted to study muscle damage and repair, 20 males ran for 35 minutes on a downhill treadmill. The participants, who were not trained runners, were pre-treated with deer antler velvet or a placebo 14 days prior to the run. The subjected treated with deer velvet showed that their creatine kinase levels, a marker of muscle damage, was significantly lower than the control group. Also, muscle soreness on average was reported to be gone 24 hours before subjects in control.
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
According to an article published by Business Insider, between 20 to 40 percent of professional MLB and NFL athletes admit to purchasing and using deer antler spray (also called “deer antler velvet”). They hope to benefit from its performing-enhancing effects. (1) Some famous athletes turn to deer antler spray in hopes of promoting growth of new tissue cells or gaining strength due to more easily putting on lean muscle mass.
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
Chondroitin sulfate is a compound of connective tissues that are usually found in cartilage. Glucosamine sulfate is a natural building block for the growth and maintenance of healthy cartilage. Since osteoarthritis is caused by the deterioration of the cartilage in the bone joints, a daily supplement of deer antler velvet can help to stimulate the repair of deteriorated bone cartilage with healthy doses of chondroitin sulfate and glucosamine sulfate.
Sourced from New Zealand, Piping Rock’s IGF-1+ extra strength Deer Antler Velvet Spray taps into ancient practices famously exploring male virility.** Each spray contains the beneficial amino acids, peptides, proteins and insulin-like growth factor-1 (IGF-1+) naturally found in deer velvet, making this spray a popular choice among athletes, fitness enthusiasts and those who are looking to support muscle strength, stamina, vitality and overall male performance.**
All groups experienced a significant improvement in strength. But the deer antler powder group showed the greatest increase in isokinetic knee extensor strength and endurance. However, it’s possible that this was due to exercise program rather than using the deer antler powder. None of the men in any group showed evidence of endocrine, red cell mass or VO2max changes. Therefore, researchers concluded that the “findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet.” (12) On the other hand, this was a small study, with only 12-13 men in each group. This means that further testing is needed to confirm the validity of the results.

Deer velvet might have an effect due to the hormones it may contain, including testosterone, androstenedione, and dehydroepiandrosterone. Research in rats, using elk velvet antler, suggested the substance may have an androgen-like effect. The antlers are ground into powder, which people take by mouth. Dosage varies by brand, but a recent study used 215 mg per day. Some distributers, though, recommend dosages ranging from 250 mg to as high as 3000 mg (3 g) per day. So talk with your doctor before you start using deer velvet.
Shake bottle before each use. Take 14 drops under the tongue 3 times per day. Hold for 20 seconds before swallowing for best results. This allows the formula to penetrate through your endocrine glands. Then the active molecules are then released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability!
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