A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
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A study by Chen found that deer antler velvet inhibits monoamine oxidase activity in the liver and brain tissues of aged mice. Monoamine-oxidase inhibitors prevent breakdown of monoamine neurotransmitters such as norepinephrine and serotonin. Antler apparently allows these vital neurotransmitters to be available longer to the brain structure, enhancing mood.
Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 
Mental Capacity and Alertness: If you’re tired of feeling like you’re experiencing life through a fog, Deer Antler Velvet can help fade the fog and give you the clarity of a good night’s sleep combined with a week’s vacation. You come at things sharp and focused. Instead of struggling to remember things words, decisions, insights and just your general alertness are sharpened.
Finding the time to workout is often the biggest challenge that I have, which I’m sure a lot of you can relate to. Some weeks it’s easier to find the time than others. The problem with that is on those weeks it’s nearly impossibly to find that time, my body tends to lose what I’ve gained in the weeks that I do find the time. But that’s changed recently since I’ve started using this new supplement. It’s called IGF-1 Plus™ Formula. Since I’ve been taking IGF-1, it has been quite evident that its had a positive effect on my exercising. I feel strength and stamina that I’ve never felt before. Also my pump seems to be more phenomenal than ever! My strength has steadily increased over the six months that I’ve been spraying this under my tongue as directed daily. What’s been extremely impressive is those weeks in which I come back when I’ve been unable to workout for a week or more. I simply don’t lose what I’ve accomplished like I had before. It was almost like starting back at square on before I started using IGF-1, but now it’s like I can pick up right where I left off before! Another thing that I’d like to mention about this formula is that I feel it’s really helped my memory and my stress level. That’s a welcomed added bonus which I hadn’t counted on. Just to put this all in terms anyone can understand, let me say this… I would take this IGF-1 for simply the results I’ve been able to achieve and maintain in the gym. But add to that how it’s helped my mind, memory, and stress level, I can honestly say that you couldn’t pay me to stop taking it!!
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
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This is a full spectrum extraction of one of the most profound substances in the anti-aging and longevity category. Deer Antler Essence is a premiere tonic formulation for the rejuvenation of Yin Essence, Yang Essence, and blood. Deer Antler is a prized tonic in the East that provides deep nourishment of Jing Essence. Considered a Yang tonic, it provides physical, sexual, and creative energy by nourishing the root energy of the body. It also is extremely powerful for nourishing bone marrow and building blood.

As this supplement is derived from 'deer', the two most commonly used species of deer in mainland China include the Sika deer Cervus nippon Temminck and Red Deer Cervus elaphus Linnaeus; these species may be relevant.[1] 'Farming' of deers for antlers includes raising deer and sawing off the antlers under analgesia,[2][3] the annual yeild appears to be 120-150 tonnes and deer are not usually killed as antlers are capable of full regeneration.[3]
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IGF-1 is currently on the World Anti-Doping Agency’s prohibited list due to how it gives athletes an unfair advantage in terms of building strength and muscle mass. (7) However, it’s still legal to use supplements that may provide IGF-1 or similar effects. Most of the studies that show positive results from using deer antler supplements have used high doses. And some have tested the product on animals (mice or rats) rather than humans.

Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.

A friend of mine gave me a bottle of your product about a month ago and I started taking it and, within a week, I started to feel energized at all hours of the day. In addition, as an actor I noticed an improvement in my memory. Most recently, I have seen a dramatic re-shaping of my body. I am gaining muscle mass and I have not trained or worked out in months! As a avid body builder most of my life, I noticed increased muscle mass without exercising, fat loss without dieting, higher energy levels, lower blood pressure, lower LDL cholesterol, younger and thicker skin, hair re-growth, wrinkles disappearing, sharper vision and bearing and of course increased memory retention…
The FDA considers deer antler spray (or deer antler velvet) to be a dietary supplement. This means it doesn’t need to be extensively studied and regulated like medications. For this reason, it can be hard to tell what the actual concentration of active ingredients or IGF-1 is in various supplements. Plus products can differ quite a bit from one brand to another in terms of their purity and effectiveness.
Research in Korea, New Zealand and China has shown that deer antler velvet can stimulate the immune system. Extracts of deer antler velvet were variously shown to increase macrophage activity, stimulate the production of lymphocytes and increase the number of red and white blood cells. Each of these effects may directly complement the body’s ability to resist or fight disease and so promote and maintain health and an associated feeling of well being.
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
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