The FDA considers deer antler spray (or deer antler velvet) to be a dietary supplement. This means it doesn’t need to be extensively studied and regulated like medications. For this reason, it can be hard to tell what the actual concentration of active ingredients or IGF-1 is in various supplements. Plus products can differ quite a bit from one brand to another in terms of their purity and effectiveness.
As men and women get older, they naturally start producing less Human Growth Hormone (HGH). So levels of IGF-1 also decline with age. The liver produces IGF-1 when HGH is released. HGH is converted to IGF-1. Aside from someone’s age, IGF-1 levels will vary depending on a person’s sex (men generally have more), level of activity, their diet, genetics and lifestyle.
Its got a bunch of stuff in it, don't miss that link above about the constituents. But, overall it contains a large amount of peptides and minerals that work synergistically with unique compounds such as hyaluronic acid and growth factors to elicit many of the effects and results. Firstly we will outline the most scientifically backed uses of deer antler velvet. Read on and make your own conclusions from the evidence supplied in the rest of this article.
I have not felt much differently since I started taking the deer antler however I did notice that when I do the arm bike I can do it faster and longer without weakness. Now you would say so big deal. For me that is a huge difference that I am tracking. I NEVER was good on the arm bike even when I was in shape it felt more labored. I am horribly out of shape for me and yet I can do this with comfortable effort. I also have taken the REM product Anna Nova health offers. Now this is where I DO notice a difference again but much more that the daily effect. My sleep has regulated to where most nights I have been able to sleep at least 5-6hrs straight. I have done that in the past. What I notice is that my body actually FEELS rested like i went into a deeper sleep. I have tried everything to sleep. Some things that are suppose to help actually work the opposite. Most all drugs have horrible effects on me and I NEVER wake up rested. I wake up foggy doppy and irritable-if I sleep. I have to say something about this works. Maybe it effects my body chemistry in manner it needs. I don’t know but its not because I WANT it to work. I have taken all this stuff tried all this stuff expecting failure. I have not slept well my whole life. Since the head injury even if I do sleep I’m not rested nor do I feel that my body relaxes. Since I have taken this after two weeks I noticed a big difference. 5hrs for most people is horrible- for me its good 6 is great and my ideal sleep. I am staying on it for another couple months to see if I feel or notice any other differences. As far as helping “heal” my body WIM hof cold exposure works the best for my brain so far. Brain injury/neck injury people are different from those without. We have dysfunctional nerves neurotransmitters and path waves that cause things to happen that we need to find other ways to fix. Drs just don’t listen and pay attention to people who are in tune with their bodies. Its too bad cause they could learn a lot from us.
"Unlike steroids, which are small, cholesterol-based hormones, protein-based hormones or growth factors can easily be destroyed," he wrote in an email. Cohen guesses that even if you consume high levels of IGF-1, most if not all of the substance would be destroyed after hitting the acid in our stomach and before entering the blood system, which is how compounds we ingest reach the muscles. "This is also why you have to inject insulin instead of just eating insulin pills," he added.
From cave people to you and me. Deer antler is easily consumed as a nutritional source for over 2000 years of recorded history, and no doubt long prior to the written word. Old school energy for modern stress. Used as a trophy from hunters, deer antler has been used as a superfood high in unique protein that will strengthen tissues and increase resistance to physical stress. Later, you'll see more about how that has become science today.
On January 30, 2013, Vijay Singh professional PGA Tour golfer was caught unaware and openly admitted to the personal use of deer antler spray which contained a banned substance at the time. A week later the World Anti-Doping Agency (WADA) lifted the ban on deer antler spray, but with urgency, "Deer Antler Velvet Spray may contain IGF-1 and WADA recommends therefore that athletes be extremely vigilant with this supplement because it could lead to a positive test."  The consensus opinion of leading endocrinologists concerning any purported claims and benefits "is simply that there is far too little of the substance in even the purest forms of the spray to make any difference,"  and "there is no medically valid way to deliver IGF-1 orally or in a spray." 
In a double blind study (Edelman, 2000), 54 patients with arthritis in the knee were given deer antler velvet or a placebo and assessed at 1, 3 and 6 months. Patients treated with deer antler velvet showed improvement in pain and physical global assessment at 3 and 6 months. No significant improvement was observed for the placebo group for any of the parameters examined.
Tonic Adaptogen* - This is a fancy concept that references the research into supplements that elicit a strengthening effect on the body and its systems.* They are tonic in action and stimulate clean holistic energy and prevent fatigue while helping us to overcome stress and maintain strong immune systems.* Due to some of the following actions we will see that this stress adaptation is generally physical in nature.
As this supplement is derived from 'deer', the two most commonly used species of deer in mainland China include the Sika deer Cervus nippon Temminck and Red Deer Cervus elaphus Linnaeus; these species may be relevant. 'Farming' of deers for antlers includes raising deer and sawing off the antlers under analgesia, the annual yeild appears to be 120-150 tonnes and deer are not usually killed as antlers are capable of full regeneration.
“I would like to thank you and your scientists for developing IGF-1. I am a 74 year old post Polio survivor, and IGF-1 has given me more relief and benefits than any product I have tried. IGF-1 is wonderful, it has improved my mobility and given me pain relief like no other product. I also have high sugar that used to range from 180-210, now my sugar is steady at 130. Along with stabilizing my sugar, IGF-1 has also lowered my blood pressure. As an experiment I went off IGF-1 for one month to see if it was doing all this good for me. My pain and loss of mobility returned until I began to use IGF-1 again. IGF-1 is truly a wonderful product, thank you for developing this miracle worker!”
I am a 68 year old grandmother of four. My friend introduced me to this wonderful product from Nutronics Labs, called IGF-1. I have been taking it for three months now and I have never felt better in my life! I am able to play with my grandchildren without getting tired and my arthritis pain has seemed to diminish completely. This product truly is a miracle! I will never go without it. I have told all my friends and they are also spraying IGF-1 now. We are your biggest fan club.
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In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.