Bottom line: Rogol says it’s “extremely unlikely” that deer antler in any form could offer athletes a boost. “Deer antlers do contain growth factors,” he explains. But it’s a huge leap of faith to talk about an extract doing anything beneficial for human beings, whether it’s slowing aging, developing muscle, or repairing tendons, he adds. Opinions like Rogol’s are one reason the FDA and anti-doping agencies haven’t yet taken steps to ban deer antler products that contain IGF-1.
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
Russian and Japanese researchers have conducted experiments using deer antler extract and found that it appears to lower blood pressure in both human subjects and laboratory animals. A series of clinical case studies (Albov, 1969) were conducted in which the effects of Pantocrin on cardiac patients were assessed. In one test involving 32 subjects with high blood pressure caused by cardiac disease, early onset menopause or obesity, blood pressure was lowered in 81% of patients. In another study involving 13 patients with hypotension caused by disorders of heart muscle activity, blood pressure was lowered for 84% of patients.
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
One of the leading companies in the world that manufacturers deer antler spray is called Nutronics Labs. According to information posted on their website, they have been making deer antler supplements for two decades. They state that their deer antler products range in concentration/strength from about 25,000ng (nanograms)–200,000ng of IGF-1. According to studies done by Nutronics Labs, deer antler powders appear to be less concentrated with IGF-1. They also may be poorly absorbed compared to deer antler extract.

Research in Korea, New Zealand and China has shown that deer antler velvet can stimulate the immune system. Extracts of deer antler velvet were variously shown to increase macrophage activity, stimulate the production of lymphocytes and increase the number of red and white blood cells. Each of these effects may directly complement the body’s ability to resist or fight disease and so promote and maintain health and an associated feeling of well being.
This is a full spectrum extraction of one of the most profound substances in the anti-aging and longevity category. Deer Antler Essence is a premiere tonic formulation for the rejuvenation of Yin Essence, Yang Essence, and blood. Deer Antler is a prized tonic in the East that provides deep nourishment of Jing Essence. Considered a Yang tonic, it provides physical, sexual, and creative energy by nourishing the root energy of the body. It also is extremely powerful for nourishing bone marrow and building blood.
In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]