Most of the world's supply of velvet antler comes from Sika deer, red deer and elk or wapiti, including a large deer ranching industry in New Zealand. New Zealand is the world’s largest producer of velvet, producing 450-500 tons of red deer velvet antler annually.[1] China produces 400 tons of predominantly Sika deer velvet antler annually. Russia produces 80 tons annually. United States and Canada each produce 20 tons annually.[2]
We know about growth factors, such as IGF-1, which are responsible for promoting healthy hormones. It is the synergy of all the constituents that help these growth factors work better. And this is why our deer antler velvet is so awesome! If you go read other labels and check the magic "extract-ratios" and micro-nanogram amounts, you'll discover something interesting:
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
Deer antler velvet can help slow the aging process and possibly even increase longevity due to the IGF-1 present in deer antler velvet. Aging occurs because our DNA becomes damaged throughout our lives and the damages accumulate over time. The damaged nuclear DNA can either directly cause the aging process by increasing cell dysfunction or it can indirectly cause the aging process by increasing programmed cell death (apoptosis) or increasing the number of cells which are unable to divide any further (cell senescence).
Deer antler spray — a supplement commonly used in the fitness and sports industries that has a long history of use in Eastern medicine — is pretty much as strange as it sounds. Derived from the tissue found inside deer antlers, it’s reported to work by providing IGF-1 (insulin-like growth factor), a natural growth hormone found inside the human body that has potential to increase muscle mass and support recovery from injuries.
Using deer antler velvet benefits sexual functions and libido by helping to increase gonadotropin hormones which include luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Luteinizing hormone (LH) and follicle-stimulating hormone are hormones that stimulate the sex glands. The stimulation of the sex glands is pivotal for sexual reproduction. Without the presence of the gonadotropin hormones, the sexual organs will fail at their purpose and the individual will be considered infertile. As the deer antler velvet promotes an increase in LH, the LH causes the testes to produce more testosterone.
A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study. 
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