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Researchers believe that the imbalance between cartilage erosion and regeneration in osteoarthritis suffers is caused by a lack of glycosaminoglycans. Glycosaminoglycans play a vital role in the structural integrity of cartilage. The compound appears to inhibit enzymes that deplete cartilage nutrition. Chondroitin sulfate molecules are long chains of sugars and sulfur that create tiny spaces filled with fluid. These spaces protect and cushion joints.
Data is limited. Two studies (n=40 and 168) investigating the efficacy of elk velvet antler supplementation on rheumatoid arthritis found no effect, while a study conducted in people with osteoarthritis (n=53) reported symptomatic relief among participants. The small sample sizes may result in the trials being underpowered to detect effects.25, 28, 29
Powdered velvet antler is available in capsule form from health shops. As a general tonic and to fight fatigue, the recommended dosage is usually 1 or 2 capsules (250 to 350 milligrams each) per day. For conditions such as osteoarthritis, higher doses may be used under supervision of a health practitioner. The effects of velvet antler gradually accumulate and are typically seen 8 to 12 weeks.
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Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor).