There is some evidence that deer antler spray may work for improving performance and physique. However, it seems that an individual needs to take very high doses in order for these benefits to occur. In studies where the supplement was effective, injections of very concentrated extracts were used. Injections may be the most effective, and likely the only, way that deer antler works. This is because IGF-1 is mostly destroyed when it passes through the digestive system. Because of this, swallowing deer antler supplements would practically be useless.
As this supplement is derived from 'deer', the two most commonly used species of deer in mainland China include the Sika deer Cervus nippon Temminck and Red Deer Cervus elaphus Linnaeus; these species may be relevant.[1] 'Farming' of deers for antlers includes raising deer and sawing off the antlers under analgesia,[2][3] the annual yeild appears to be 120-150 tonnes and deer are not usually killed as antlers are capable of full regeneration.[3]

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Deer antler velvet is rich in insulin-like growth factor 1 (IGF-1) which is a growth hormone produced naturally in the liver as a response to human growth hormone (HGH) stimulation. This is a key factor in how deer antler velvet can help to promote muscle growth. IGF-1 works on the body by promoting the growth of healthy, lean skeletal muscles. This growth of healthy muscle mass can be influenced by IGF-1's tendency to increase muscle protein and muscle DNA content. There is evidence to suggest that IGF-1 acts on muscle tissue by promoting protein synthesis and the proliferation of satellite cells, both of which result in skeletal muscle growth due to the enlargement of the muscle cells.
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
Deer antler velvet can act as a natural adaptogen, restoring homeostasis to an unbalanced body by helping where it is needed. Deer antler velvet has an effect on many systems of the body given its complex chemical composition. The active ingredients in deer antler velvet are mostly precursors that are required by the body to process substances that maintain its health and wellbeing.
Most of the world's supply of velvet antler comes from Sika deer, red deer and elk or wapiti, including a large deer ranching industry in New Zealand. New Zealand is the world’s largest producer of velvet, producing 450-500 tons of red deer velvet antler annually.[1] China produces 400 tons of predominantly Sika deer velvet antler annually. Russia produces 80 tons annually. United States and Canada each produce 20 tons annually.[2]
"Unlike steroids, which are small, cholesterol-based hormones, protein-based hormones or growth factors can easily be destroyed," he wrote in an email. Cohen guesses that even if you consume high levels of IGF-1, most if not all of the substance would be destroyed after hitting the acid in our stomach and before entering the blood system, which is how compounds we ingest reach the muscles. "This is also why you have to inject insulin instead of just eating insulin pills," he added.

Raise Only Male Hormones* - Seriously, what if you are a woman? This is once again incorrect as it does not directly raise only male hormones for a majority of the population, especially women. But if you have a lagging gladular system due to overwhelming stress and fatigue than the adaptogen capabilities may allow your lagging glandular system to function more appropriately, hence you may correct for proper hormone functioning.*
An acute dose of 2,000mg/kg Deer Velvet Antler to rats (human equivalent dose of 320mg/kg) has failed to show toxic signs over 14 subsequent days of observation, and a 90 day trial with daily dosing of 1,000mg/kg did not show any significant toxicological symptoms of haemotological signs; a decrease in liver weight was noted in males, but under histological examination it appeared to be benign.[38] Another rat toxicological study using 10% of the diet as Deer Velvet Antler during gestation and after birth noted that there were no apparent teratogenic effects on the rat pups and that serum AST (indicative of liver damage) was actually decreased 50% relative to control with no effect on γ-GT (another liver enzyme).[30]
Shake well before use. As a dietary supplement, spray 2 times under tongue, 3 times per day. Hold the liquid under your tongue without swallowing for 20 seconds. This allows the formula to penetrate through your endocrine glands. Then the active molecules are then released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability! Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication.
In what might be the most important study done in the United States, a group of scientists took 32 male weight lifters and gave half of them New Zealand Deer Antler Velvet and half of them a placebo for 10 weeks. While the placebo group didn't show any difference in bench or squat tests, those given deer antler velvet saw an increase of 4 percent on the bench press and 10.1 percent on the squat test as compared to the placebo group. The scientists also reported that there was a "significant improvement in aerobic capacity" with the group that was taking deer antler velvet.
Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes.[18] In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars.[19][20] In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." [21]
I am a cancer survivor from 1993. I started using IGF-1 in October 2001. The Cancer I had in ’93 had a 0 survivor rate, but through God, nutrition and supplements I healed. Still, I was left with intense pain, chronic fatigue, and other damage done by the cancer. IGF-1 is now one supplement I will not do without, no way, period. IGF-1 has virtually helped me rebuild my body from the vast cancer induced damage. I am now not only pain free, I am also surfing at 46 years young with the teenagers and physically cannot be held back. I have increased lean muscle mass, the silver in my hair has disappeared and my vision has returned to full focus. I more than highly recommend IGF-1 to everyone wishing to be youthful in body and mind. Thank you and congratulations on the most important find in our century.

In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 

People with osteoarthritis take chondroitin sulphate as an anti-inflammatory and velvet antler contains a high concentration of this compound, as well as significant amounts of glucosamine sulphate. Both appear to inhibit the depletion of bone and cartilage. The use of velvet antler in treating rheumatoid arthritis is being studied at the University of Calgary and the University of Alberta.
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IGF-1 is currently on the World Anti-Doping Agency’s prohibited list due to how it gives athletes an unfair advantage in terms of building strength and muscle mass. (7) However, it’s still legal to use supplements that may provide IGF-1 or similar effects. Most of the studies that show positive results from using deer antler supplements have used high doses. And some have tested the product on animals (mice or rats) rather than humans.
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