In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
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Research in Korea, New Zealand and China has shown that deer antler velvet can stimulate the immune system. Extracts of deer antler velvet were variously shown to increase macrophage activity, stimulate the production of lymphocytes and increase the number of red and white blood cells. Each of these effects may directly complement the body’s ability to resist or fight disease and so promote and maintain health and an associated feeling of well being.
Velvet antler is the whole cartilaginous antler in a precalcified growth stage of the Cervidae family including the species of deer, elk, moose and caribou. Velvet antler is covered in a hairy, velvet-like "skin" known as velvet and its tines are rounded, because the antler has not calcified or finished developing. Velvet antler preparations are sold in China as part of Traditional Chinese medicine, and in the United States and some other countries as a dietary supplement.
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There is an increasing amount of scientific evidence supporting the benefits of deer antler velvet from decades of research carried out in Russia, Korea, China, Japan, Australia and New Zealand. This research has given credibility to deer antler velvet’s traditional usage and validated recommendations for its inclusion as an everyday health supplement. Almost 250 papers have been published since 1930 on the manufacture, composition and biochemical effect of deer antler velvet. Studies on deer antler velvet and the corresponding findings are described below.
A study (Yudin and Dobyrakov, 1974) on the effect of deer antler velvet extract on the static load-bearing capacity of subjects found that those who took the extract increased the time of work by 2-4 seconds compared to the control group. In tests of dynamic work using a veloergometer, the subjects who took the extract increased the work output 4 to 5 times more than the control group.
Elk velvet antlers have been shown to contain chondroitin sulfate. This has a growth-promoting effect on cells throughout the body, which helps with recovery. This includes cells in the gut. It is believed that cartilage proteoglycans regulate water retention and differentiation and proliferation of chondrocytes inside cartilage tissue. Four types of collagen (I, II, III, and X) have also been identified in deer antlers. The collagen may provide benefits including rebuilding damaged parts of the GI tract, skin and joints. This might be beneficial for preventing or helping to treat leaky gut syndrome, which contributes to widespread symptoms.
Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass.
Suggested use: Take one tablet 20-30 minutes prior to your two main meals of the day with 8oz. glass of water. You may also use Nutronics Labs Weight Loss Plus in conjunction with any of our IGF-1 liposome spray products for optimal results. Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication.