In rats undergoing left coronary artery ligation, those with heart failure were given either Velvet Antler (Deer) or Captopril as active control for 4 weeks with a third group given water.[17] No significant changes in cardiac structure was noted with either Velvet Antlers or Captopril (with the heart tissue being enlarged after heart failure) although left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) appeared to be improved in both treatment groups to approximately the same degree and the increase in serum Brain Natiuretic Peptide (BNP) that occurred with heart failure was attenuated the same degree in both interventions.[17]
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*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.
A study conducted in rowers given 560mg Velvet Root for 10 weeks of training has failed to find improvements in rowing performance or other parameters of strength (bench press and leg press) in both sexes.[28] 1350mg of Velvet Antler twice daily (daily dose of 2,700mg) for 10 weeks was noted to increase leg strength (assessed via leg press) more than placebo with no differences in the bench press; this study had a 44% dropout rate and conclusions that can be drawn are limited.[27]
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
Even sellers of deer antler products doubt that the products could deliver IGF-1. "IGF-1 is very unstable," Dean Nieves of Florida-based Bio Lab Naturals told the Baltimore Sun. "It could not exist outside of a very controlled environment." Nieves' company therefore markets the product as a nutritional supplement. "It is just packed with nutrients," he said.
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A growing trend in western medicine is the proliferation of influences from ancient eastern medicine. Over 2,000 years ago, the Chinese were administering deer antler velvet to treat conditions ranging from serious illnesses to lack of sexual desire. After closely examining the wide range of health benefits deer antler velvet promotes, it's no wonder why the Chinese used it as a medicine for thousands of years.
Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor). 
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