According to an article published by Business Insider, between 20 to 40 percent of professional MLB and NFL athletes admit to purchasing and using deer antler spray (also called “deer antler velvet”). They hope to benefit from its performing-enhancing effects. (1) Some famous athletes turn to deer antler spray in hopes of promoting growth of new tissue cells or gaining strength due to more easily putting on lean muscle mass.
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Tribulus: An extract taken from the Mediterranean puncture vine that some cultures believe to have medicinal values. There is little clinical data surrounding the bio-physical effects of tribulus, however some people take it to enhance athletic performance, sexual ability, and improve circulation. Not much is known about the long-term consequences of tribulus consumption, however there are some indications that it may potentially lead to prostate issues in some men.

The truth? While research is limited, there’s nothing to suggest that deer antler velvet (or deer antler spray in the supplement form) actually does what it claims. In fact, there are two published studies (in real scientific journals, you can see them here and here) that suggest deer antler velvet does not (I repeat, does not) even elicit a hormonal response. What’s more, it also did not increase muscular strength or aerobic power.
A Russian study indicated that the amino acids, polypeptides and other compounds found in antler increased the survival rate of mice with cancerous tumors as much as 40 percent. In addition, a study conducted by the East-West Research Institute in Korea found that deer antler velvet appears to increase neutrophil levels in mice, which boost the body’s ability to fight injuries and disease. The mice with tumors lost less weight and suffered lower levels of kidney damage than those treated with drugs.
Data is limited. Two studies (n=40 and 168) investigating the efficacy of elk velvet antler supplementation on rheumatoid arthritis found no effect, while a study conducted in people with osteoarthritis (n=53) reported symptomatic relief among participants. The small sample sizes may result in the trials being underpowered to detect effects.25, 28, 29
Yes, the Soviets had even been involved in extensive research to ascertain the performance benefits of deer antler velvet. But they've been using it for awhile. In their country it was known in Russian folk use to be a warming and vitalizing food several hundred years ago, but with the advent of modern history, they began research nearly 90 years ago.

Elk velvet antlers have been shown to contain chondroitin sulfate. This has a growth-promoting effect on cells throughout the body, which helps with recovery. This includes cells in the gut. It is believed that cartilage proteoglycans regulate water retention and differentiation and proliferation of chondrocytes inside cartilage tissue. Four types of collagen (I, II, III, and X) have also been identified in deer antlers. The collagen may provide benefits including rebuilding damaged parts of the GI tract, skin and joints. This might be beneficial for preventing or helping to treat leaky gut syndrome, which contributes to widespread symptoms.
I am considering getting this. I have late stage lymes disease that is in my brain and nervous system and it is ruining me. I cant get help anywhere. I have gained 50 lbs even though I eat healthy after working so hard to lose 248 lbs. Its ruined my brain. I am getting very concerned I am not going to get better and have tried everything. are you still taking it since it is a year later and what have you noticed? I am 47 yr old female. If you wouldnt mind emailing me back id appreciate it. powerhouseami at gmail
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Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits.  It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels.  Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer.  Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.  
Bottom line: Rogol says it’s “extremely unlikely” that deer antler in any form could offer athletes a boost. “Deer antlers do contain growth factors,” he explains. But it’s a huge leap of faith to talk about an extract doing anything beneficial for human beings, whether it’s slowing aging, developing muscle, or repairing tendons, he adds. Opinions like Rogol’s are one reason the FDA and anti-doping agencies haven’t yet taken steps to ban deer antler products that contain IGF-1.
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I took red mountain deer velvet and it really messed my stomach up. I now have cramps and bloating all the time plus it feels like my stomach shrank…I can’t eat like I used to. It was a big mistake to take that stuff. Do you know of any way I can get my stomach back to normal??? Can you recommend someone who knows a lot about deer velvet?? I have been suffering terribly since I took that junk…it’s been about 2 years now!!!! My stomach has never been the same since I took that poison!!
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