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An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization, and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes). This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.
The company has found that powders have only about a 15–20 percent absorption rate of IGF-1. This is due to how the digestive system breaks down the powder. Nutronics states that their “proprietary sublingual spray delivery system” is superior to many competitors because it offers “enhanced bioavailability” of IGF-1. They also point out that “it is not the milligrams of Deer Antler Velvet in the product, it’s the content of IGF-1 and other Growth Factors in Deer Antler Velvet, that makes the difference.”(6)
The IGF-1 in deer antler velvet can help increase the body's natural healing by affecting cell repair and growth. When an injury or surgery occurs that leaves a wound on the body, the wound is healed naturally by the cells which line the wound. Those cells multiply and rejoin over time. Using deer antler velvet can help promote faster cell repair and growth so that the wound can heal at a faster rate which means less time being injured or sore.
More recent tests (Slievert, 2003) confirm deer antler velvet’s effects on muscle strength and endurance. In a randomized, double blind, placebo controlled experiment, 18 males entered a 10 week strength training program. Those who took deer antler velvet showed an increase in maximal aerobic capacity, an increase in strength in the bench press and leg squat, and decrease in body fat relative to the placebo group.
Deer antler spray — a supplement commonly used in the fitness and sports industries that has a long history of use in Eastern medicine — is pretty much as strange as it sounds. Derived from the tissue found inside deer antlers, it’s reported to work by providing IGF-1 (insulin-like growth factor), a natural growth hormone found inside the human body that has potential to increase muscle mass and support recovery from injuries.
Joint Health & Injury Recovery* - Due to certain constituents recognized by the government one will benefit by better joint health, plus the content of proteins similar to our own bodily structures are plentiful within deer antler supplements, such as type II collagen.* Another involved and interesting cellular activator known as hyaluronic acid has many additional benefits for repair and regeneration.
S.W.A.T.S. Fitness and Performance was a dietary supplement company that sold deer antler spray and other products. The owners began distributing their products to NCAA and NFL athletes in 2008. The controversy initially started in March 30, 2009 when Alabama athletic officials sent a cease-and-desist letter to the company's owner that stated: "Refrain from using current student-athletes to endorse products. Refrain from contacting current student-athletes. Refrain from giving or selling products to current student-athletes."  The letter was then sent again in 2012.
“My name is Sidney Outlaw and I’m a professional Mixed Martial Arts Fighter. For some time during and after my workouts, I had been struggling with training alongside some of the world’s best UFC fighters. Then I started using a Nutronics Labs supplement. Since I’ve been using this product, I have more energy during my workouts and my post workout recovery has improved tremendously. I’m able to train with my MMA team and also my memory has improved which helps with my ability to focus.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.