In a study on diabetic mice given topical wounds (scalpel and scissors to create a cricle; diabetes tends to reduce wound healing rates and thus diabetic rats are a good research model for wound closure rates) where either a control cream or one containing 400mcg Velvet Antler (Elk; water soluble extract) noted that there was less angiogenesis and a trend towards less inflammation assocaited with Velvet Antler cream while on day 7 wounds treated with the Antler cream were significantly smaller than control. One 3.2kDa protein has been noted to possess wound healing properties, which are dose-dependent and have been noted to improve wound healing induced by burns at 0.05-0.1% of solution and in vitro at 10-40mcg/mL.
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
According to an article published by Business Insider, between 20 to 40 percent of professional MLB and NFL athletes admit to purchasing and using deer antler spray (also called “deer antler velvet”). They hope to benefit from its performing-enhancing effects. (1) Some famous athletes turn to deer antler spray in hopes of promoting growth of new tissue cells or gaining strength due to more easily putting on lean muscle mass.
Chondroitin sulfate is a compound of connective tissues that are usually found in cartilage. Glucosamine sulfate is a natural building block for the growth and maintenance of healthy cartilage. Since osteoarthritis is caused by the deterioration of the cartilage in the bone joints, a daily supplement of deer antler velvet can help to stimulate the repair of deteriorated bone cartilage with healthy doses of chondroitin sulfate and glucosamine sulfate.
Currently, IGF-1 is banned by both the World Anti-Doping Agency and the Food and Drug Administration (FDA). However, deer antler spray seems to provide only very small amounts of IGF-1. This is why it’s no longer considered illegal. Insulin-like growth factor is also naturally found in other animal-derived foods, including eggs, milk and red meat. Some experts believe that the amount of IGF-1 obtained from using deer antler products is really not much more than from eating these foods.
As this supplement is derived from 'deer', the two most commonly used species of deer in mainland China include the Sika deer Cervus nippon Temminck and Red Deer Cervus elaphus Linnaeus; these species may be relevant. 'Farming' of deers for antlers includes raising deer and sawing off the antlers under analgesia, the annual yeild appears to be 120-150 tonnes and deer are not usually killed as antlers are capable of full regeneration.
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