Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure.
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Many people from many cultures use it. Throughout history it has been used by the American Indians, Europeans, Romans, Russians, and Asians as an alcohol extract. Often it was easily made into soups for its strengthening bone broth protein full of raw material for tissues, joints and bone. The most complete ancient literature is the Chinese texts, which give it top classification for over 2,000 years.
All groups experienced a significant improvement in strength. But the deer antler powder group showed the greatest increase in isokinetic knee extensor strength and endurance. However, it’s possible that this was due to exercise program rather than using the deer antler powder. None of the men in any group showed evidence of endocrine, red cell mass or VO2max changes. Therefore, researchers concluded that the “findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet.” (12) On the other hand, this was a small study, with only 12-13 men in each group. This means that further testing is needed to confirm the validity of the results.
I am a 52 years old from New York City. I have been taking anti-depressants and sleeping pills for many years. Since my husband and I started taking IGF-1 and the sleep miracle product, I was able to stop the anti-depressants and also thanks to the sleep miracle I am able to get a great nights rest without sleeping pills. Not to mention, both our libidos have been fantastic! WOW! We feel like newly weds again.
Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass.
Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims. The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA. As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."
Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves, although testosterone may be the primary growth factor. Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.
In a study on diabetic mice given topical wounds (scalpel and scissors to create a cricle; diabetes tends to reduce wound healing rates and thus diabetic rats are a good research model for wound closure rates) where either a control cream or one containing 400mcg Velvet Antler (Elk; water soluble extract) noted that there was less angiogenesis and a trend towards less inflammation assocaited with Velvet Antler cream while on day 7 wounds treated with the Antler cream were significantly smaller than control. One 3.2kDa protein has been noted to possess wound healing properties, which are dose-dependent and have been noted to improve wound healing induced by burns at 0.05-0.1% of solution and in vitro at 10-40mcg/mL.
IGF-1 is currently on the World Anti-Doping Agency’s prohibited list due to how it gives athletes an unfair advantage in terms of building strength and muscle mass. (7) However, it’s still legal to use supplements that may provide IGF-1 or similar effects. Most of the studies that show positive results from using deer antler supplements have used high doses. And some have tested the product on animals (mice or rats) rather than humans.
Although previously found on the World Anti-Doping Agency's list of banned substances, Deer Antler Spray was removed in 2013 when it was deemed completely safe and legal to consume prior to athletic activity. Deer Antler Spray has been known to speed up the rehabilitation process of injuries, especially injuries effecting cartilage. It has also been known to boost endurance and strength, increase muscle mass, decrease fat, and raise one's testosterone levels, thus increasing libido. The use of Deer Antler Velvet Spray has been linked to several athletes, including football star Ray Lewis, who is rumored to have used it following an injury to his tricep in 2013.
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This is a full spectrum extraction of one of the most profound substances in the anti-aging and longevity category. Deer Antler Essence is a premiere tonic formulation for the rejuvenation of Yin Essence, Yang Essence, and blood. Deer Antler is a prized tonic in the East that provides deep nourishment of Jing Essence. Considered a Yang tonic, it provides physical, sexual, and creative energy by nourishing the root energy of the body. It also is extremely powerful for nourishing bone marrow and building blood.
While Lentini admits sales have picked up, he says he's been hurt by the perception in the recent baseball letter, which told players that deer antler velvet could be contaminated with methyltestosterone, a banned steroid. The connection is based on the fact that David Vobora tested positive for the steroid after using antler spray. He won a $5.4 million judgment against the company that made the spray.
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Finding the time to workout is often the biggest challenge that I have, which I’m sure a lot of you can relate to. Some weeks it’s easier to find the time than others. The problem with that is on those weeks it’s nearly impossibly to find that time, my body tends to lose what I’ve gained in the weeks that I do find the time. But that’s changed recently since I’ve started using this new supplement. It’s called IGF-1 Plus™ Formula. Since I’ve been taking IGF-1, it has been quite evident that its had a positive effect on my exercising. I feel strength and stamina that I’ve never felt before. Also my pump seems to be more phenomenal than ever! My strength has steadily increased over the six months that I’ve been spraying this under my tongue as directed daily. What’s been extremely impressive is those weeks in which I come back when I’ve been unable to workout for a week or more. I simply don’t lose what I’ve accomplished like I had before. It was almost like starting back at square on before I started using IGF-1, but now it’s like I can pick up right where I left off before! Another thing that I’d like to mention about this formula is that I feel it’s really helped my memory and my stress level. That’s a welcomed added bonus which I hadn’t counted on. Just to put this all in terms anyone can understand, let me say this… I would take this IGF-1 for simply the results I’ve been able to achieve and maintain in the gym. But add to that how it’s helped my mind, memory, and stress level, I can honestly say that you couldn’t pay me to stop taking it!!
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
In an experiment (Gerard, 2004) conducted to study muscle damage and repair, 20 males ran for 35 minutes on a downhill treadmill. The participants, who were not trained runners, were pre-treated with deer antler velvet or a placebo 14 days prior to the run. The subjected treated with deer velvet showed that their creatine kinase levels, a marker of muscle damage, was significantly lower than the control group. Also, muscle soreness on average was reported to be gone 24 hours before subjects in control.
On January 30, 2013, Vijay Singh professional PGA Tour golfer was caught unaware and openly admitted to the personal use of deer antler spray which contained a banned substance at the time. A week later the World Anti-Doping Agency (WADA) lifted the ban on deer antler spray, but with urgency, "Deer Antler Velvet Spray may contain IGF-1 and WADA recommends therefore that athletes be extremely vigilant with this supplement because it could lead to a positive test."  The consensus opinion of leading endocrinologists concerning any purported claims and benefits "is simply that there is far too little of the substance in even the purest forms of the spray to make any difference,"  and "there is no medically valid way to deliver IGF-1 orally or in a spray." 
Physical Vigor and Stamina: You don’t have to be an athlete to appreciate more energy and stamina. You may have long hours at the office, at home with kids, or at school, in training or partying. Without the energy you need to get through the day, nothing is fun-even the fun stuff. Unlike caffeine or energy boosting drinks which give you a temporary boost, Deer Antler Velvet changes you from the inside out, making increased vigor and stamina a part of your body’s natural response to the demands you place on it.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.