When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
There is some evidence that deer antler spray may work for improving performance and physique. However, it seems that an individual needs to take very high doses in order for these benefits to occur. In studies where the supplement was effective, injections of very concentrated extracts were used. Injections may be the most effective, and likely the only, way that deer antler works. This is because IGF-1 is mostly destroyed when it passes through the digestive system. Because of this, swallowing deer antler supplements would practically be useless.
An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization, and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes). This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.
Suggested use: Take one tablet 20-30 minutes prior to your two main meals of the day with 8oz. glass of water. You may also use Nutronics Labs Weight Loss Plus in conjunction with any of our IGF-1 liposome spray products for optimal results. Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication.