One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
Deer antlers are the only mammalian bone structures to regenerate completely every year.1 Deer antler velvet is the epidermis covering the inner structure of the growing bone and cartilage, which develops into antlers.2 This tissue grows each spring on male Cervus sp. (North American elk and red deer) and should be removed by a veterinarian or certified farmer. The ethics, including use of local anesthetics, and procedures of harvesting antler velvet have been reported.3, 4, 5, 6 Velvet yield depends on several factors, including season, parasites, or injury.7 After removal of the deer velvet, it is collected and then frozen or dried prior to its manufacture into various "medicinal" forms including powders, extracts, teas, capsules, and tablets. Each part of elk velvet contains varying compounds, but the deer antler velvet contains the largest concentrations of those found to be beneficial. (Antler also has been sold by the slice). Heating during processing may reduce or destroy the purported beneficial effects of velvet antler. Various preparation methods, including freeze-drying and non-heat-producing methods have been reported.8, 9, 10, 11, 12, 13
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These are required in enzyme and catalytic cellular functions as well as being the raw material for tissues. Growth factors are known to boost cellular functioning and uptake of nutrients This helps our own growth, regeneration of tissues and injury recovery, as well as a slowing and preventing the effects of agings. Many hormones are closely associated with IGF-1
Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass.
There must be a reason to is use and a booming world industry that garners the attention of several researchers and scientist in many countries. Modern understanding has greatly advanced our knowledge of velvet antler. We know by its composition and the knowledge of the structure and function of the plenitude of constituents which work together, like a symphony, to create an efficacious supplement that yields a multitude of benefits.
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IGF-1 is currently on the World Anti-Doping Agency’s prohibited list due to how it gives athletes an unfair advantage in terms of building strength and muscle mass. (7) However, it’s still legal to use supplements that may provide IGF-1 or similar effects. Most of the studies that show positive results from using deer antler supplements have used high doses. And some have tested the product on animals (mice or rats) rather than humans.
The IGF-1 found in deer antler spray is derived from deer antler velvet, the tissue found inside the deer's antlers before they fully harden. Since deer antlers grow incredibly fast, it is not surprising that the horns are rich in IGF-1. This is a naturally-occurring form of IGF-1, meaning it is not made in a lab. As a result, deer antler velvet is considered a dietary supplement by the Food and Drug Administration, and unlike synthesized drugs, the product does have to be proven safe or effective before it's sold to the public.
According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.
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In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup. In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs. Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).
Other uses include treatment of high cholesterol, high blood pressure, migraines, muscle aches and pains, asthma, indigestion, weak bones (osteoporosis), headache, liver and kidney disorders, cold hands and feet, soreness and weakness in the lower back and knees, chronic skin ulcers, and overactive bladder. It is also used to promote youthfulness, sharpen thinking skills, protect the liver from toxins, stimulate production and circulation of blood, and increase the number of red blood cells.
Deer antler velvet can play a pivotal role in helping to not only relieve the symptoms of diseases that affect joints, such as osteoarthritis, they can possibly eliminate them entirely. The way it may do this is through the introduction of chondroitin sulfate and glucosamine sulfate into the body. Both of these compounds are abundant in deer antler velvet.