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Data is limited. Two studies (n=40 and 168) investigating the efficacy of elk velvet antler supplementation on rheumatoid arthritis found no effect, while a study conducted in people with osteoarthritis (n=53) reported symptomatic relief among participants. The small sample sizes may result in the trials being underpowered to detect effects.25, 28, 29

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Deer antler velvet can help slow the aging process and possibly even increase longevity due to the IGF-1 present in deer antler velvet. Aging occurs because our DNA becomes damaged throughout our lives and the damages accumulate over time. The damaged nuclear DNA can either directly cause the aging process by increasing cell dysfunction or it can indirectly cause the aging process by increasing programmed cell death (apoptosis) or increasing the number of cells which are unable to divide any further (cell senescence).

My name is William Gucciardo. I am fifty-four years old and have been exercising and taking nutritional supplementation for many years. I was recently introduced to IGF-1, and have been taking it for three weeks. Although I have been working out six days a week for the past several years, I have recently noticed an increase in upper body muscle tone and overall strength and endurance. I have also noticed that minor stiffness that I daily experienced upon arising in the morning is gone. My body feels stronger with an overall feeling of well being. I can only attribute these changes to the addition of IGF-1 to my supplementation program, as this is the only change that I have recently made. I do not know what further benefits I will receive from taking IGF-1 daily. If you are willing to try something new with the possibility of improving your health and well being, I would recommend trying this product.

Deer antler velvet is supposed to help you build muscle. It allegedly elevates levels of IGF-1, an important hormone that helps you pack on mass. As “side effects” you also should see improvements in strength and endurance. And some products even claim it speeds recovery, which is why it was linked to Ray Lewis who earlier suffered an apparent season-ending injury, and yet has played and performed at a high level in the playoffs.
One double-blind study published in the International Journal of Sports Nutrition and Exercise Metabolism tested whether or not deer antler velvet powder or extract had an impact on aerobic performance, endurance and “trainability of muscular strength” compared to a placebo. The subjects were adult males. They were given either a placebo, or deer antler extract or powder supplementation over a  10-week period while undergoing a strength-building routine. The men were measured for muscular strength, endurance, and VO2max before and after using deer antler. These results were determined by measuring circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume.
In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]
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