No direct reports of chronic wasting disease (CWD) related to deer velvet supplementation have been published. However, several Web sites contain disclaimers mentioning the possibility of the disease being present in antler products. The CDC has not yet found a relationship between CWD and any neurological disease that affects humans with deer velvet use.
Chondroitin sulfate is a compound of connective tissues that are usually found in cartilage. Glucosamine sulfate is a natural building block for the growth and maintenance of healthy cartilage. Since osteoarthritis is caused by the deterioration of the cartilage in the bone joints, a daily supplement of deer antler velvet can help to stimulate the repair of deteriorated bone cartilage with healthy doses of chondroitin sulfate and glucosamine sulfate.
According to an article published by Business Insider, between 20 to 40 percent of professional MLB and NFL athletes admit to purchasing and using deer antler spray (also called “deer antler velvet”). They hope to benefit from its performing-enhancing effects. (1) Some famous athletes turn to deer antler spray in hopes of promoting growth of new tissue cells or gaining strength due to more easily putting on lean muscle mass.
From cave people to you and me. Deer antler is easily consumed as a nutritional source for over 2000 years of recorded history, and no doubt long prior to the written word. Old school energy for modern stress. Used as a trophy from hunters, deer antler has been used as a superfood high in unique protein that will strengthen tissues and increase resistance to physical stress. Later, you'll see more about how that has become science today.
Well it’s been a little bit since I last talked to you Rick Lentini so I thought I would send you an email just to say hello, fill you in on how things are going out here, and see how everything is on your side of the world. Out here is all the same, its hot during the day, a little chilly at night and dusty all the time. Without breaching OPSEC I can tell you that our mission is going somewhat smooth and morale is at an all time high. We have a lot of moving parts and long days but at the end of every day the guys and myself are ready to attack the gym and get some well deserved rest just so we can wake up and do it all over again. Cpl Trousdale* and myself have made great progress in spreading the good word on IGF and have a lot of Marines, Soldiers, and Airmen, all coming back saying they are surprised with how effective IGF has been in not only their lifting but everyday work and play. OORAH to IGF! As for me, well I am just as pleased as everyone else, but more so that I’ve had the opportunity to communicate with you directly, it’s been a great pleasure. Semper Fidelis.
New Zealand research reports that although the mechanism is unknown, deer antler velvet shows strong anti-inflammatory effects. Recent clinical tests suggest oral ingestion of glycosaminoglycan-peptide complex, or components such as chondroitin sulfate and glucosamine sulfate — both found in deer antler velvet — may help stimulate cartilage repair.
My knee also started to hurt as well as I was acquiring plantar fasciitis and I couldn’t figure out how to keep myself from hurting until a co-worker told me about Velvet Deer Antler from the sports news. He showed me your site and as a pure skeptic, ordered my 10,000ng of IGF-1. After the FIRST WEEK, I noticed that my plantar fasciitis had practically gone away WITHOUT wearing night splints, my knee had stopped inflaming, and no longer needed a full on brace (as seen in the picture).
On January 30, 2013, Vijay Singh professional PGA Tour golfer was caught unaware and openly admitted to the personal use of deer antler spray which contained a banned substance at the time. A week later the World Anti-Doping Agency (WADA) lifted the ban on deer antler spray, but with urgency, "Deer Antler Velvet Spray may contain IGF-1 and WADA recommends therefore that athletes be extremely vigilant with this supplement because it could lead to a positive test."  The consensus opinion of leading endocrinologists concerning any purported claims and benefits "is simply that there is far too little of the substance in even the purest forms of the spray to make any difference,"  and "there is no medically valid way to deliver IGF-1 orally or in a spray." 
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
The answer is that deer antler velvet is just another fat burner. Another cell volumizer. Another body-toning shoe. It’s fitness marketing at it’s finest—playing off a goal you desire (gaining more muscle and size) and drawing unsubstantiated and wildly exaggerated claims. There’s nothing miraculous about deer antler spray. And after a closer look at the product, there’s really—well—nothing to it at all.
Even sellers of deer antler products doubt that the products could deliver IGF-1. "IGF-1 is very unstable," Dean Nieves of Florida-based Bio Lab Naturals told the Baltimore Sun. "It could not exist outside of a very controlled environment." Nieves' company therefore markets the product as a nutritional supplement. "It is just packed with nutrients," he said.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.