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Although previously found on the World Anti-Doping Agency's list of banned substances, Deer Antler Spray was removed in 2013 when it was deemed completely safe and legal to consume prior to athletic activity. Deer Antler Spray has been known to speed up the rehabilitation process of injuries, especially injuries effecting cartilage. It has also been known to boost endurance and strength, increase muscle mass, decrease fat, and raise one's testosterone levels, thus increasing libido. The use of Deer Antler Velvet Spray has been linked to several athletes, including football star Ray Lewis, who is rumored to have used it following an injury to his tricep in 2013.
According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.
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A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.