I know of no scientific evidence to support any of the marketing claims made for these supplements. I discussed your question with Tieraona Low Dog, M.D., an internationally recognized expert in the fields of integrative medicine, dietary supplements and women’s health, and an authority on botanical medicine. She explains that IGF-1 in the velvet promotes rapid growth of the antler. Dr. Low Dog notes that the two studies examining the effects of deer antler velvet supplements taken by athletes have yielded conflicting results. One showed some improvements in endurance and knee strength in weightlifters, but the other found no differences in rowers after 10 weeks of supplementation.
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization.  In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to.  (That’s not a value judgment, just the facts.)
Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 
The message was from Neema Yazdani. Some of you might recognize Neema’s name from my most recent book, The Men’s Health Big Book: Getting Abs. Neema was a test subject that epitomized the great results you could receive with the program. As a guy that had tried just about everything during the last 12 years, Neema dropped body fat and added muscle with a simpler approach included in the book.
An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]

My name is Freddie and I’m 58 years old. About a year ago I joined a health club and began exercising. It made me a lot better physically. A few short months ago another member of the club I belong to introduced me to this wonderful product that you spray under your tongue. It’s called IGF-1 Plus™ lipospray. Years ago I had surgery on the rotator cuff of my right shoulder. Recently I started getting that same familiar pain in my left shoulder. It was difficult, if not impossible, to get a good nights sleep. The pain I was experiencing would wake me up in the middle of the night (usually 2 or more times/night). I would sleep for at least 11 or 12 hours a night. However, within a week or so after I started using IGF-1, I noticed that I wasn’t suffering in pain from my shoulder nearly as much as I had been. I also started noticing that the number of hours I was sleeping at night was steadily decreasing, but amazingly I felt better rested. Also before using this spray, I could not keep up with my wife when we would go out for walks. Now I keep up with her and it doesn’t fee like I’m trying any harder! I now only sleep 6 hours a night, feel better rested, and my shoulder has been getting stronger and rarely ever gives me trouble. I did however make the mistake of running out of my IGF-1 once. Slowly that excruciating pain was coming back and I started sleeping longer. Believe me, I’m now stocked up on it and hope I never run out again! Oh, one other improvement I’ve noticed is in my hearing. Before I would be constantly asking people to repeat themselves, which I rarely do anymore (and I don’t think it’s a coincidence)! Thank you!
We know about growth factors, such as IGF-1, which are responsible for promoting healthy hormones. It is the synergy of all the constituents that help these growth factors work better. And this is why our deer antler velvet is so awesome! If you go read other labels and check the magic "extract-ratios" and micro-nanogram amounts, you'll discover something interesting:
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Tissue Growth* - Ancient use was as a growth tonic for underdeveloping children and as a gland activator for the glandularly deficient.* It was also recommended to maturing people because of this interesting action on the body.* In modern times it has been discovered that very small amounts of key constituents, called growth factors, signal cellular structures for regeneration and growth, and are found in deer antler velvet extract itself and in larger amounts within the circulating blood of those who take it.*

Researchers believe that the imbalance between cartilage erosion and regeneration in osteoarthritis suffers is caused by a lack of glycosaminoglycans. Glycosaminoglycans play a vital role in the structural integrity of cartilage. The compound appears to inhibit enzymes that deplete cartilage nutrition. Chondroitin sulfate molecules are long chains of sugars and sulfur that create tiny spaces filled with fluid. These spaces protect and cushion joints.
In an experiment (Gerard, 2004) conducted to study muscle damage and repair, 20 males ran for 35 minutes on a downhill treadmill. The participants, who were not trained runners, were pre-treated with deer antler velvet or a placebo 14 days prior to the run. The subjected treated with deer velvet showed that their creatine kinase levels, a marker of muscle damage, was significantly lower than the control group. Also, muscle soreness on average was reported to be gone 24 hours before subjects in control.
Deer antler velvet is the tissue that covers the bone and cartilage that develop into deer (and elk) antlers. It has been harvested for centuries and used traditionally to increase strength, boost the immune system, and counter the effects of stress. Now it’s promoted to improve athletic performance; raise testosterone levels to increase sex drive, fertility and erectile function in men; as well as to reduce the signs of aging and treat problems ranging from high cholesterol, high blood pressure, asthma and osteoporosis to migraine headaches, indigestion, and many more.
IGF-1 can help slow this aging process down by increasing the telomere length of our DNA. Telomeres are a protective "cap" at the end of each strand of our DNA which prevents the DNA from becoming damaged. DNA becomes damaged as the telomeres grow shorter with age. As more DNA strands become damaged, cells in our bodies can no longer function properly which results in many medical conditions, diseases, and even death. This is how IGF-1 can help longevity. It does this by promoting healthy DNA strands to keep our cellular functions optimal.
Well it’s been a little bit since I last talked to you Rick Lentini so I thought I would send you an email just to say hello, fill you in on how things are going out here, and see how everything is on your side of the world. Out here is all the same, its hot during the day, a little chilly at night and dusty all the time. Without breaching OPSEC I can tell you that our mission is going somewhat smooth and morale is at an all time high. We have a lot of moving parts and long days but at the end of every day the guys and myself are ready to attack the gym and get some well deserved rest just so we can wake up and do it all over again. Cpl Trousdale* and myself have made great progress in spreading the good word on IGF and have a lot of Marines, Soldiers, and Airmen, all coming back saying they are surprised with how effective IGF has been in not only their lifting but everyday work and play. OORAH to IGF! As for me, well I am just as pleased as everyone else, but more so that I’ve had the opportunity to communicate with you directly, it’s been a great pleasure. Semper Fidelis.

L-Arginine: An amino acid usually found in red meats that is important for the body’s ability to manufacture proteins. L-Arginine has been used to treat conditions like high blood pressure, congestive heart failure, blocked arteries, and erectile dysfunction. L-Arginine is safe for most people, however it should not be taken by women that are pregnant or breastfeeding.
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