Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits. It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels. Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer. Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.
In rats undergoing left coronary artery ligation, those with heart failure were given either Velvet Antler (Deer) or Captopril as active control for 4 weeks with a third group given water. No significant changes in cardiac structure was noted with either Velvet Antlers or Captopril (with the heart tissue being enlarged after heart failure) although left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) appeared to be improved in both treatment groups to approximately the same degree and the increase in serum Brain Natiuretic Peptide (BNP) that occurred with heart failure was attenuated the same degree in both interventions.
In a study on diabetic mice given topical wounds (scalpel and scissors to create a cricle; diabetes tends to reduce wound healing rates and thus diabetic rats are a good research model for wound closure rates) where either a control cream or one containing 400mcg Velvet Antler (Elk; water soluble extract) noted that there was less angiogenesis and a trend towards less inflammation assocaited with Velvet Antler cream while on day 7 wounds treated with the Antler cream were significantly smaller than control. One 3.2kDa protein has been noted to possess wound healing properties, which are dose-dependent and have been noted to improve wound healing induced by burns at 0.05-0.1% of solution and in vitro at 10-40mcg/mL.
Deer antler velvet is supposed to help you build muscle. It allegedly elevates levels of IGF-1, an important hormone that helps you pack on mass. As “side effects” you also should see improvements in strength and endurance. And some products even claim it speeds recovery, which is why it was linked to Ray Lewis who earlier suffered an apparent season-ending injury, and yet has played and performed at a high level in the playoffs.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days. When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.
Most of the world's supply of velvet antler comes from Sika deer, red deer and elk or wapiti, including a large deer ranching industry in New Zealand. New Zealand is the world’s largest producer of velvet, producing 450-500 tons of red deer velvet antler annually. China produces 400 tons of predominantly Sika deer velvet antler annually. Russia produces 80 tons annually. United States and Canada each produce 20 tons annually.
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Shake bottle before each use. Take 14 drops under the tongue 3 times per day. Hold for 20 seconds before swallowing for best results. This allows the formula to penetrate through your endocrine glands. Then the active molecules are then released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability!