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In 168 persons with stable Rheumatoid Arthritis but present pain (25-100mm on the VAS rating scale) given either 1g of Velvet Antler from Elk or placebo for 6 months noted that there were no significant differences between placebo and Velvet Antler in regards to pain. Another study by the same research group using a smaller sample (n=40) and graded doses of 430mg, 860mg, and 1290mg daily noted that there was a dose-dependent trend towards reduced pain symptoms but this was not statistically significant.
According to an article in Sports Illustrated, Lewis spoke by telephone after his injury with Mitch Ross, co-owner of the supplement company S.W.A.T.S. (Sports with Alternatives to Steroids) to ask about treatments that could speed his recovery. Sports Illustrated reported that among Ross’ recommendations were deer antler pills to “rebuild your brain via your small intestines.” In addition to recommending the pills, Ross reportedly also told Lewis to spray deer antler extract under his tongue. Lewis has denied following this advice, and Ravens’ management has said that the star player has never flunked a drug test.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.