An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization, and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes). This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.
Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass.
All male members of the deer family, including elk, moose and reindeer (caribou), grow a new set of antlers each year’from scratch, in just a matter of months’then shed them at the end of the annual mating season. The ability to regenerate such large appendages each year is unique to this family among mammals and rare in the animal kingdom as a whole (horns, in contrast to antlers, are permanent and cannot be regrown). Understanding how it happens could have significant implications for human medicine, particularly in the fields of wound healing and organ regeneration.