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As men and women get older, they naturally start producing less Human Growth Hormone (HGH). So levels of IGF-1 also decline with age. The liver produces IGF-1 when HGH is released.  HGH is converted to IGF-1. Aside from someone’s age, IGF-1 levels will vary depending on a person’s sex (men generally have more), level of activity, their diet, genetics and lifestyle.
Even sellers of deer antler products doubt that the products could deliver IGF-1. "IGF-1 is very unstable," Dean Nieves of Florida-based Bio Lab Naturals told the Baltimore Sun. "It could not exist outside of a very controlled environment." Nieves' company therefore markets the product as a nutritional supplement. "It is just packed with nutrients," he said.

But when it comes to sprays or pills, there’s little evidence that deer antler offers performance enhancing benefits of any kind, says Alan Rogol, M.D., an endocrinologist at the University of Virginia. Rogol is also part of a small team of doctors that assists anti-doping agencies in determining if and when athletes can use certain controversial substances.


Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.
Deer antlers have been closely linked to IGF-1, which is another term for insulin. This has been well received in eastern medicine as an anti-aging and bodybuilding product. Because it’s also a known natural growth hormone, it’s said to aid in muscle development by enhancing strength and improving recovery time. This is what attracts bodybuilders to this product.
Studies have found that deer antlers themselves contain a highly concentrated amount of essential trace minerals, fatty acids, amino acids and growth factors that can all support the immune system. This includes the gastrointestinal tract, where the majority of the immune system is found. Antlers contain minerals such as: calcium, phosphorus, magnesium, iron, potassium and sodium in addition to numerous minor components.
I have been using deer velvet to treat my arthritis for over 10 years. When I run out for a couple weeks, the pains increase and I lose mobility in my joints. And when I continue with the supplement, the pain goes away and the mobility comes back. Additionally it helps my over feeling of well being (I suspect it balances my hormones). I am a fan. I use 1000 mg of day of antler farms velvet from Ne ... Show Full Comment
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).

Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass. 

All groups experienced a significant improvement in strength. But the deer antler powder group showed the greatest increase in isokinetic knee extensor strength and endurance. However, it’s possible that this was due to exercise program rather than using the deer antler powder. None of the men in any group showed evidence of endocrine, red cell mass or VO2max changes. Therefore, researchers concluded that the “findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet.” (12) On the other hand, this was a small study, with only 12-13 men in each group. This means that further testing is needed to confirm the validity of the results.
In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 
Blood Pressure: Almost 30% of Americans (28.7%) have high blood pressure. If you’re 60 years of age, 65.4% of your age group has it. If you’re black, 33.5% vs. 28.7% of whites, have high blood pressure. It’s a very common problem-and only gets worse as we age. So why should you worry about your blood pressure? Because high blood pressure is the cause of heart attacks, stroke, blindness, kidney disease and failure and death to name a few reasons. Did you know that 5 million people in US have high blood pressure, including those getting treated for it? But wait-almost 40 million people don’t know they have it, aren’t getting it treated or can’t control it adequately! Are you one of them? Ask your doctor. Deer Antler Velvet has been shown to reduce high blood pressure naturally, without side effects and without interfering with any medication you’re already on.
Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.

I just wanted to let you know that April 29, 2011 I was diagnosed with ALL Leukemia. I just recently, finished my chemo therapy after a 2 year regimen. I have stayed very active though out the 2 years but the drugs were very difficult to tolerate at times. My love is Cycling, I have raced at a high level for many years. I started using the product to help me regain my strength. I have been using the Nutronics IGF-1 for 2 months and my endurance and energy have improved dramatically. I look forward to the continued use and the gains that IGF-1 provides. I appreciate your support.
I would like to express my deepest gratitude for IGF-1. I am 54 years old and until now I have suffered with chronic fatigue, depression and insomnia. After being on IGF-1 for less than 1 month, my energy levels are back up and improving more everyday. I once took 3 naps per day just to function, I do not need naps anymore. I once needed prescription sleeps aids, now I sleep all night long without medication, thanks to IGF-1. It is hard to put into words all that IGF-1 is doing for me, so I will just say I feel like a new man with vitality that I have not felt in 25 years.
Dr. Low Dog also reports that a chronic wasting disease in deer, elk and moose is the only recognized prion (infectious protein) disease of wild animals and has been found in 15 states and two provinces in Canada. (Prion diseases in wild animals are similar to bovine spongiform encephalopathy, better known as mad cow disease, in cattle.) No known cases of neurological disease have been seen in humans who have taken deer antler velvet supplements, but a 2009 study sponsored by the National Institutes of Neurological Diseases and Stroke and the U.S. Department of Agriculture concluded that the possibility remains.
More recent tests (Slievert, 2003) confirm deer antler velvet’s effects on muscle strength and endurance. In a randomized, double blind, placebo controlled experiment, 18 males entered a 10 week strength training program. Those who took deer antler velvet showed an increase in maximal aerobic capacity, an increase in strength in the bench press and leg squat, and decrease in body fat relative to the placebo group.

Deer antler spray products are not cheap. Expect that buying a high-quality product will set you back about $60–$100 per bottle. When taken as directed, each bottle should last you about one month. You don’t need to refrigerate the spray. However, keep it away from very hot temperatures to preserve the chemical composition of the product. Manufacturers claim that you can start experiencing benefits within 3–4 days. However, results definitely differ from one person to the next.
As this supplement is derived from 'deer', the two most commonly used species of deer in mainland China include the Sika deer Cervus nippon Temminck and Red Deer Cervus elaphus Linnaeus; these species may be relevant.[1] 'Farming' of deers for antlers includes raising deer and sawing off the antlers under analgesia,[2][3] the annual yeild appears to be 120-150 tonnes and deer are not usually killed as antlers are capable of full regeneration.[3]
Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor). 
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