First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization.  In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to.  (That’s not a value judgment, just the facts.)

In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21]  

with cardio and strength. Keep in mind I was active my whole life and fairly strong for my size and age. My endurance was crazy and I often out worked guys 18-40 without thinking twice. Since the injury I have more pain and less endurance. I never slept good but since the injury “night time” sleep is horrible at times. up for over 24hrs. Though I am not great the next day I still functioned can work a full day. IN general I sometimes fatigue and have to nap after a workout -which is a pathetic workout compared to the workouts I used to do.

Even sellers of deer antler products doubt that the products could deliver IGF-1. "IGF-1 is very unstable," Dean Nieves of Florida-based Bio Lab Naturals told the Baltimore Sun. "It could not exist outside of a very controlled environment." Nieves' company therefore markets the product as a nutritional supplement. "It is just packed with nutrients," he said.
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People with osteoarthritis take chondroitin sulphate as an anti-inflammatory and velvet antler contains a high concentration of this compound, as well as significant amounts of glucosamine sulphate. Both appear to inhibit the depletion of bone and cartilage. The use of velvet antler in treating rheumatoid arthritis is being studied at the University of Calgary and the University of Alberta.
One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed.[26] The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.[27]
Now, you’ll probably read a lot about the power of IGF-1 in many reports about Ray Lewis. And while it’s true that IGF-1 is illegal in man-made form, let’s not mistake illegal products (because they are synthetic) with guaranteed amazing results. IGF-1 can have a significant impact on your body, but it’s not that easy to get the levels you need from deer antler. In fact, given what’s in a typical bottle, it is damn near impossible.
Aphrodisiac* - For a long time the alcohol extract has been used to strengthen reproductive organ function, but modern studies of deer antler velvet results are inconclusive concerning women and from men. Although some people do report benefit in intimacy, this may be because of the performance, blood circulation and stress adaptation effects.* So in other words, if your supplement doesn't have the alcohol extract in it don't expect the benefits of supplements made with it.*
“I've been taking deer antler since 2012 so I've been taking it for years and I definitely believe in it. And for recovery after hard, intense workouts, deer antler is a must. Go to AntlerFarms.com, definitely get the [deer antler velvet extract tablets] and the [deer antler velvet capsules]. Take those two in combination and you will feel great.”* 

Currently, IGF-1 is banned by both the World Anti-Doping Agency and the Food and Drug Administration (FDA). However, deer antler spray seems to provide only very small amounts of IGF-1. This is why it’s no longer considered illegal. Insulin-like growth factor is also naturally found in other animal-derived foods, including eggs, milk and red meat. Some experts believe that the amount of IGF-1 obtained from using deer antler products is really not much more than from eating these foods.
High Quality Long Jack (scientifically; Eurycoma Longifolia, learn more on WebMD) is known to help your body naturally increase testosterone levels (and raise libido), boost cardio endurance, build lean muscle, and reduce body fat. Combined with our Premium (A-Grade) Deer Antler Velvet, Ultra Plus w/Long Jack can really help you take your workouts to another level and stand tall!
I am a 52 years old from New York City. I have been taking anti-depressants and sleeping pills for many years. Since my husband and I started taking IGF-1 and the sleep miracle product, I was able to stop the anti-depressants and also thanks to the sleep miracle I am able to get a great nights rest without sleeping pills. Not to mention, both our libidos have been fantastic! WOW! We feel like newly weds again.

Elk velvet antlers have been shown to contain chondroitin sulfate. This has a growth-promoting effect on cells throughout the body, which helps with recovery. This includes cells in the gut. It is believed that cartilage proteoglycans regulate water retention and differentiation and proliferation of chondrocytes inside cartilage tissue. Four types of collagen (I, II, III, and X) have also been identified in deer antlers. The collagen may provide benefits including rebuilding damaged parts of the GI tract, skin and joints. This might be beneficial for preventing or helping to treat leaky gut syndrome, which contributes to widespread symptoms.

A study conducted in rowers given 560mg Velvet Root for 10 weeks of training has failed to find improvements in rowing performance or other parameters of strength (bench press and leg press) in both sexes.[28] 1350mg of Velvet Antler twice daily (daily dose of 2,700mg) for 10 weeks was noted to increase leg strength (assessed via leg press) more than placebo with no differences in the bench press; this study had a 44% dropout rate and conclusions that can be drawn are limited.[27]

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Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims.[12] The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)][36] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA.[12][14][15][16][17] As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
Even more intriguing is how the stags manage to regrow their antlers. Scientists have found stem cells at the bases of antlers’essentially ‘blank’ cells that can develop into many different types of cell, such as a skin cell or a cartilage cell. If they could find out what triggers the stem cells and controls their development into antlers, the knowledge could be applied to the regeneration of human limbs and organs. Scientists know that the shedding is initiated by a fall in the hormone testosterone, a change linked to an increase in day length, and they think oestrogen may be a key cellular regulator. However, much more research on a molecular level is required to unravel what is clearly an intricate process.
Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 
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