Even more intriguing is how the stags manage to regrow their antlers. Scientists have found stem cells at the bases of antlers’essentially ‘blank’ cells that can develop into many different types of cell, such as a skin cell or a cartilage cell. If they could find out what triggers the stem cells and controls their development into antlers, the knowledge could be applied to the regeneration of human limbs and organs. Scientists know that the shedding is initiated by a fall in the hormone testosterone, a change linked to an increase in day length, and they think oestrogen may be a key cellular regulator. However, much more research on a molecular level is required to unravel what is clearly an intricate process.
This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.
According to an article in Sports Illustrated, Lewis spoke by telephone after his injury with Mitch Ross, co-owner of the supplement company S.W.A.T.S. (Sports with Alternatives to Steroids) to ask about treatments that could speed his recovery. Sports Illustrated reported that among Ross’ recommendations were deer antler pills to “rebuild your brain via your small intestines.” In addition to recommending the pills, Ross reportedly also told Lewis to spray deer antler extract under his tongue. Lewis has denied following this advice, and Ravens’ management has said that the star player has never flunked a drug test.
The first question to ask, is why? Why are you considering this supplement? A supplement is not intended to fix a crappy diet or poor exercise program. A supplement is intended to be just that, a supplement to your existing good diet/good exercise program. And if you’re eating a well-rounded diet, then there’s really no need for supplementation at all.
A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
"I was diagnosed with Muscular Dystrophy at the age of 3. For those of you who do not know Muscular Dystrophy is a disease that essentially means muscles with bad nutrition. My results with this product have been phenomenal. I've definitely noticed an increase in energy, definitely strength. I went from 12 reps to 43 reps in just five weeks. There is something special about this product."*

Physical Vigor and Stamina: You don’t have to be an athlete to appreciate more energy and stamina. You may have long hours at the office, at home with kids, or at school, in training or partying. Without the energy you need to get through the day, nothing is fun-even the fun stuff. Unlike caffeine or energy boosting drinks which give you a temporary boost, Deer Antler Velvet changes you from the inside out, making increased vigor and stamina a part of your body’s natural response to the demands you place on it.
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization.  In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to.  (That’s not a value judgment, just the facts.)

The IGF-1 found in deer antler spray is derived from deer antler velvet, the tissue found inside the deer's antlers before they fully harden. Since deer antlers grow incredibly fast, it is not surprising that the horns are rich in IGF-1. This is a naturally-occurring form of IGF-1, meaning it is not made in a lab. As a result, deer antler velvet is considered a dietary supplement by the Food and Drug Administration, and unlike synthesized drugs, the product does have to be proven safe or effective before it's sold to the public.
Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.

In a double blind study (Edelman, 2000), 54 patients with arthritis in the knee were given deer antler velvet or a placebo and assessed at 1, 3 and 6 months. Patients treated with deer antler velvet showed improvement in pain and physical global assessment at 3 and 6 months. No significant improvement was observed for the placebo group for any of the parameters examined.
Increase your overall energy and motivation while getting the most of your rest and recovery. Adapting to stress assist will help us better regulate our immune, nervous and adrenal systems. Adapting to stress means hormonal health. Proper use could even benefit an overactive system that is depleted, therefore promoting greater health in those with adrenal fatigue. It does so by activating the glands which secrete hormones that boost recovery and regeneration.
Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims.[12] The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)][36] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA.[12][14][15][16][17] As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21]