When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
Supplements are best used in situations where an individual is unable to get their nutrients from their diet. Perhaps an individual has an allergy or intolerance, for example lactose. They are unable to consume milk products which in turn limits their ability to get sufficient calcium and vitamin D from their diet. In that case, a supplement makes sense.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
I have not felt much differently since I started taking the deer antler however I did notice that when I do the arm bike I can do it faster and longer without weakness. Now you would say so big deal. For me that is a huge difference that I am tracking. I NEVER was good on the arm bike even when I was in shape it felt more labored. I am horribly out of shape for me and yet I can do this with comfortable effort. I also have taken the REM product Anna Nova health offers. Now this is where I DO notice a difference again but much more that the daily effect. My sleep has regulated to where most nights I have been able to sleep at least 5-6hrs straight. I have done that in the past. What I notice is that my body actually FEELS rested like i went into a deeper sleep. I have tried everything to sleep. Some things that are suppose to help actually work the opposite. Most all drugs have horrible effects on me and I NEVER wake up rested. I wake up foggy doppy and irritable-if I sleep. I have to say something about this works. Maybe it effects my body chemistry in manner it needs. I don’t know but its not because I WANT it to work. I have taken all this stuff tried all this stuff expecting failure. I have not slept well my whole life. Since the head injury even if I do sleep I’m not rested nor do I feel that my body relaxes. Since I have taken this after two weeks I noticed a big difference. 5hrs for most people is horrible- for me its good 6 is great and my ideal sleep. I am staying on it for another couple months to see if I feel or notice any other differences. As far as helping “heal” my body WIM hof cold exposure works the best for my brain so far. Brain injury/neck injury people are different from those without. We have dysfunctional nerves neurotransmitters and path waves that cause things to happen that we need to find other ways to fix. Drs just don’t listen and pay attention to people who are in tune with their bodies. Its too bad cause they could learn a lot from us.
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
Almost everyone can benefit from deer antler velvet. Our customers take deer antler velvet for many reasons - to support general health, to restore an ailing body, or to improve physical function and performance. Our client list consists of: physicians, naturopath doctors, chiropractors, physical therapists and surgeons; firefighters, police officers and soldiers; construction workers, miners and other laborers; professional athletes in football, soccer, baseball, basketball, hockey, and mixed martial arts.
"I was diagnosed with Muscular Dystrophy at the age of 3. For those of you who do not know Muscular Dystrophy is a disease that essentially means muscles with bad nutrition. My results with this product have been phenomenal. I've definitely noticed an increase in energy, definitely strength. I went from 12 reps to 43 reps in just five weeks. There is something special about this product."*
Deer antler velvet can play a pivotal role in helping to not only relieve the symptoms of diseases that affect joints, such as osteoarthritis, they can possibly eliminate them entirely. The way it may do this is through the introduction of chondroitin sulfate and glucosamine sulfate into the body. Both of these compounds are abundant in deer antler velvet.
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study. 
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