One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed.[26] The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.[27]

Although previously found on the World Anti-Doping Agency's list of banned substances, Deer Antler Spray was removed in 2013 when it was deemed completely safe and legal to consume prior to athletic activity. Deer Antler Spray has been known to speed up the rehabilitation process of injuries, especially injuries effecting cartilage. It has also been known to boost endurance and strength, increase muscle mass, decrease fat, and raise one's testosterone levels, thus increasing libido. The use of Deer Antler Velvet Spray has been linked to several athletes, including football star Ray Lewis, who is rumored to have used it following an injury to his tricep in 2013.

Both a lack of sexual desire and sexual performance issues like erectile dysfunction can be traced back to a low testosterone level. Deer antler velvet can help increase the production of hormones related to sexual functions, including testosterone and its metabolites. In this way, deer antler velvet can help as not only an aphrodisiac but also as a possible treatment for erectile dysfunction.
For those of you in your teens and 20’s, if you take this type of supplementation your body will begin to stop producing this naturally; and that right there is NOT a good thing. If you really believe you are getting some benefit from using this supplement than you will need to take more and more as your body stops making it completely (at an early age), and will most very likely have complications later, if not sooner, due to having to increase your dose. Therefore when it is found, and it is known that IGF-1, the active ingredient of why Deer Antler Velvet is used, can cause cancer, especially prostate cancer and the enlargement of other vital organs in the body, not muscles.
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An acute dose of 2,000mg/kg Deer Velvet Antler to rats (human equivalent dose of 320mg/kg) has failed to show toxic signs over 14 subsequent days of observation, and a 90 day trial with daily dosing of 1,000mg/kg did not show any significant toxicological symptoms of haemotological signs; a decrease in liver weight was noted in males, but under histological examination it appeared to be benign.[38] Another rat toxicological study using 10% of the diet as Deer Velvet Antler during gestation and after birth noted that there were no apparent teratogenic effects on the rat pups and that serum AST (indicative of liver damage) was actually decreased 50% relative to control with no effect on γ-GT (another liver enzyme).[30]

Studies have found that deer antlers themselves contain a highly concentrated amount of essential trace minerals, fatty acids, amino acids and growth factors that can all support the immune system. This includes the gastrointestinal tract, where the majority of the immune system is found. Antlers contain minerals such as: calcium, phosphorus, magnesium, iron, potassium and sodium in addition to numerous minor components.
Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.
But when it comes to sprays or pills, there’s little evidence that deer antler offers performance enhancing benefits of any kind, says Alan Rogol, M.D., an endocrinologist at the University of Virginia. Rogol is also part of a small team of doctors that assists anti-doping agencies in determining if and when athletes can use certain controversial substances.
S.W.A.T.S. Fitness and Performance was a dietary supplement company that sold deer antler spray and other products. The owners began distributing their products to NCAA and NFL athletes in 2008.[19] The controversy initially started in March 30, 2009 when Alabama athletic officials sent a cease-and-desist letter to the company's owner that stated: "Refrain from using current student-athletes to endorse products. Refrain from contacting current student-athletes. Refrain from giving or selling products to current student-athletes." [25] The letter was then sent again in 2012.[26]
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
with cardio and strength. Keep in mind I was active my whole life and fairly strong for my size and age. My endurance was crazy and I often out worked guys 18-40 without thinking twice. Since the injury I have more pain and less endurance. I never slept good but since the injury “night time” sleep is horrible at times. up for over 24hrs. Though I am not great the next day I still functioned can work a full day. IN general I sometimes fatigue and have to nap after a workout -which is a pathetic workout compared to the workouts I used to do.

In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 

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