An acute dose of 2,000mg/kg Deer Velvet Antler to rats (human equivalent dose of 320mg/kg) has failed to show toxic signs over 14 subsequent days of observation, and a 90 day trial with daily dosing of 1,000mg/kg did not show any significant toxicological symptoms of haemotological signs; a decrease in liver weight was noted in males, but under histological examination it appeared to be benign. Another rat toxicological study using 10% of the diet as Deer Velvet Antler during gestation and after birth noted that there were no apparent teratogenic effects on the rat pups and that serum AST (indicative of liver damage) was actually decreased 50% relative to control with no effect on γ-GT (another liver enzyme).
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A 2015 study published in Evidenced Based Complimentary and Alternative Medicine fed mice a diet containing 10 percent elk velvet extract (EVA) to test its effects on physical growth and bone development. Researchers measured the mice’s body weights, blood chemistry, kidney and testis/ovary functions, and bone traits weekly. They found that “Mean body weights were higher in the EVA group at 4–8 weeks in males, and at 5 weeks of age in females.” The mice fed EVA also experienced changes in kidney function and increased femoral bone length by 5 weeks old. Levels of alkaline phosphatase (ALP) increased in EVA group.
Joint Health & Injury Recovery* - Due to certain constituents recognized by the government one will benefit by better joint health, plus the content of proteins similar to our own bodily structures are plentiful within deer antler supplements, such as type II collagen.* Another involved and interesting cellular activator known as hyaluronic acid has many additional benefits for repair and regeneration.
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