A 2015 study published in Evidenced Based Complimentary and Alternative Medicine fed mice a diet containing 10 percent elk velvet extract (EVA) to test its effects on physical growth and bone development.  Researchers measured the mice’s body weights, blood chemistry, kidney and testis/ovary functions, and bone traits weekly. They found that “Mean body weights were higher in the EVA group at 4–8 weeks in males, and at 5 weeks of age in females.” The mice fed EVA also experienced changes in kidney function and increased femoral bone length by 5 weeks old. Levels of alkaline phosphatase (ALP) increased in EVA group.
If you have any existing medical condition that requires taking medication, always consult your physician before taking any new products. Discuss if deer antler spray will be safe for you to use if you have a history of serious hormonal problems, heart disease, liver or kidney disease, or any other serious condition. It’s also not wise to stop taking any medications you’ve been taking or to end physical therapy sessions/exercises because you’ve started taking deer antler spray. Always follow up with your doctor or therapist if you have questions about changing your recovery plan regarding an injury or illness.
For a long time velvet antler is recognized as a powerful tonic that naturally stimulates us with a clean and non-fatiguing energy. Not like coffee or energy drinks. This effect can be subtle, but its long term consumption benefits are profound in that we can more easily overcome and adapt to daily stress. Many types of stress depending on who we are as individuals. How much to take is important and talked about in the dosage section. Having the capability of increased resistance to physical stress is a major use to everyone. 
According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.
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A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
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