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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated Nov 1st, 2018), Cerner Multum™ (updated Nov 1st, 2018), Wolters Kluwer™ (updated Oct 31st, 2018) and others. To view content sources and attributions, please refer to our editorial policy.

The IGF-1 found in deer antler spray is derived from deer antler velvet, the tissue found inside the deer's antlers before they fully harden. Since deer antlers grow incredibly fast, it is not surprising that the horns are rich in IGF-1. This is a naturally-occurring form of IGF-1, meaning it is not made in a lab. As a result, deer antler velvet is considered a dietary supplement by the Food and Drug Administration, and unlike synthesized drugs, the product does have to be proven safe or effective before it's sold to the public.


As an international entertainer, it is important for me to keep up with my physical appearance and overall health. Those attributes contribute to longer lasting energy while performing and good stage presence. My physical appearance lacked from being overweight, which in turn effected my energy while performing. I fought with both for many years. This fight caused me to lose out on booking for shows, sponsorships and photo shoots.
“I would like to thank you and your scientists for developing IGF-1. I am a 74 year old post Polio survivor, and IGF-1 has given me more relief and benefits than any product I have tried. IGF-1 is wonderful, it has improved my mobility and given me pain relief like no other product. I also have high sugar that used to range from 180-210, now my sugar is steady at 130. Along with stabilizing my sugar, IGF-1 has also lowered my blood pressure. As an experiment I went off IGF-1 for one month to see if it was doing all this good for me. My pain and loss of mobility returned until I began to use IGF-1 again. IGF-1 is truly a wonderful product, thank you for developing this miracle worker!”
If you want help building muscle and losing fat, you can apply to work with me one-on-one. You’ll receive professionally designed workouts, have access to me and some of the best strength and nutrition coaches to ask your questions and get the help you need. Best of all? The first month is risk free so you can ensure that the program is right for you.
Other studies reported an increase in heart strength and volume of blood pumped, while cardiac output, heart rate, mean arterial pressure, pulse pressure, central venous pressure and other parameters remained unchanged. Researchers suggest that the polysaccharides in antler may reduce the blood’s tendency to clot, improving circulation, decreasing stroke risk and boosting general cardiovascular health. Researchers theorize that the deer antler velvet may improve blood supply to muscles or act as an anti-inflammatory, allowing athletes to recover faster from training sessions.
An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]
Velvet Antler is a supplement derived from powdered or crushed antlers, most commonly from deer (and thus referred to as Deer Velvet Antler) although Elk have also been used. They have been used in Traditional Chinese Medicine.[1] The base of the antler is referred to as Cervus (in reference to deers), Lu Jiao Pan, Zhen Zhu Pan, as well as Lu Hua Pan and appears to have been traditionally used for cardiovascular disease, gynecological problems, immunological deficiencies, blood cancers, tissue repair and health promotion.[1] The specific part used is the antler base; when the antler is sawed off the base temporarily remains until the regeneration of the new antler pushes it off which occurrs occasionally in the wild. Traditional usage involves using the base and macerating it in wine or decocting it with water for oral consumption.[1]
Deer antlers are the only mammalian bone structures to regenerate completely every year.1 Deer antler velvet is the epidermis covering the inner structure of the growing bone and cartilage, which develops into antlers.2 This tissue grows each spring on male Cervus sp. (North American elk and red deer) and should be removed by a veterinarian or certified farmer. The ethics, including use of local anesthetics, and procedures of harvesting antler velvet have been reported.3, 4, 5, 6 Velvet yield depends on several factors, including season, parasites, or injury.7 After removal of the deer velvet, it is collected and then frozen or dried prior to its manufacture into various "medicinal" forms including powders, extracts, teas, capsules, and tablets. Each part of elk velvet contains varying compounds, but the deer antler velvet contains the largest concentrations of those found to be beneficial. (Antler also has been sold by the slice). Heating during processing may reduce or destroy the purported beneficial effects of velvet antler. Various preparation methods, including freeze-drying and non-heat-producing methods have been reported.8, 9, 10, 11, 12, 13
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.

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The FDA considers deer antler spray (or deer antler velvet) to be a dietary supplement. This means it doesn’t need to be extensively studied and regulated like medications. For this reason, it can be hard to tell what the actual concentration of active ingredients or IGF-1 is in various supplements. Plus products can differ quite a bit from one brand to another in terms of their purity and effectiveness.
Deer antler velvet may help to increase macrophage activity. Macrophages are a type of white blood cell (immunity cell) that digests cellular debris, foreign substances, cancer cells, and other microorganisms. Macrophages help to stimulate defense mechanisms in the body by recruiting immune cells such as lymphocytes. With this increased number of white blood cells, your immunity system becomes strengthened and will have a better chance at fighting off a sickness or infection.
Adaptogen: Adaptogens are natural metabolic regulators that increase a person’s ability to adapt to environmental factors-like pollution, smoke, stress, toxins etc. and to avoid damage from those factors. In other words, adaptogens literally help your body “adapt” to the environment without any side effects. If you’re living in the real world, with external or internal stressors, adaptogens help your body change in order to cope with the stressors.

In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 
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