An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]
I know of no scientific evidence to support any of the marketing claims made for these supplements. I discussed your question with Tieraona Low Dog, M.D., an internationally recognized expert in the fields of integrative medicine, dietary supplements and women’s health, and an authority on botanical medicine. She explains that IGF-1 in the velvet promotes rapid growth of the antler. Dr. Low Dog notes that the two studies examining the effects of deer antler velvet supplements taken by athletes have yielded conflicting results. One showed some improvements in endurance and knee strength in weightlifters, but the other found no differences in rowers after 10 weeks of supplementation.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
From cave people to you and me. Deer antler is easily consumed as a nutritional source for over 2000 years of recorded history, and no doubt long prior to the written word. Old school energy for modern stress. Used as a trophy from hunters, deer antler has been used as a superfood high in unique protein that will strengthen tissues and increase resistance to physical stress. Later, you'll see more about how that has become science today.
Deer antler velvet is used for its purported ability to raise testosterone levels to treat decreased libido (low sex drive), infertility, and erectile dysfunction in men.  It is used in combination with other herbs to treat sexual dysfunction and hormonal dysfunction in men and women.  It is used to treat conditions resulting from deficient kidneys.  Some people use it because of its reputed benefit as an aphrodisiac and muscle strength enhancer.  It is also sometimes prescribed to help alleviate withdrawal symptoms in the treatment of morphine addiction.  
Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits.  It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels.  Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer.  Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.  
Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes.[18] In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars.[19][20] In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." [21]
We know about growth factors, such as IGF-1, which are responsible for promoting healthy hormones. It is the synergy of all the constituents that help these growth factors work better. And this is why our deer antler velvet is so awesome! If you go read other labels and check the magic "extract-ratios" and micro-nanogram amounts, you'll discover something interesting:
If you have any existing medical condition that requires taking medication, always consult your physician before taking any new products. Discuss if deer antler spray will be safe for you to use if you have a history of serious hormonal problems, heart disease, liver or kidney disease, or any other serious condition. It’s also not wise to stop taking any medications you’ve been taking or to end physical therapy sessions/exercises because you’ve started taking deer antler spray. Always follow up with your doctor or therapist if you have questions about changing your recovery plan regarding an injury or illness.
Deer antler velvet is the tissue that covers the bone and cartilage that develop into deer (and elk) antlers. It has been harvested for centuries and used traditionally to increase strength, boost the immune system, and counter the effects of stress. Now it’s promoted to improve athletic performance; raise testosterone levels to increase sex drive, fertility and erectile function in men; as well as to reduce the signs of aging and treat problems ranging from high cholesterol, high blood pressure, asthma and osteoporosis to migraine headaches, indigestion, and many more.
Published research has shown that IGF-1 can produce similar results to growth hormone. The catch? If you do the math from the study, a 150-pound man (that’s a pretty small guy, so a bigger man would need more) would have to take more than 25 million nanograms just to experience the growth hormone-like effects of more muscle, less fat, and faster recovery.

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Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.
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Deer antler velvet can help slow the aging process and possibly even increase longevity due to the IGF-1 present in deer antler velvet. Aging occurs because our DNA becomes damaged throughout our lives and the damages accumulate over time. The damaged nuclear DNA can either directly cause the aging process by increasing cell dysfunction or it can indirectly cause the aging process by increasing programmed cell death (apoptosis) or increasing the number of cells which are unable to divide any further (cell senescence).
I’ve been taking IGF-1 Plus for 10 years. This is the most amazing product I have ever seen in all my years as a personal trainer and professional bodybuilder. I would recommend this product to anyone whether they were just trying to achieve maximum health or compete in any competitive sports. I feel like I could compete for Mr. Olympia at my age by taking this wonderful product.

Other studies reported an increase in heart strength and volume of blood pumped, while cardiac output, heart rate, mean arterial pressure, pulse pressure, central venous pressure and other parameters remained unchanged. Researchers suggest that the polysaccharides in antler may reduce the blood’s tendency to clot, improving circulation, decreasing stroke risk and boosting general cardiovascular health. Researchers theorize that the deer antler velvet may improve blood supply to muscles or act as an anti-inflammatory, allowing athletes to recover faster from training sessions.
If you want help building muscle and losing fat, you can apply to work with me one-on-one. You’ll receive professionally designed workouts, have access to me and some of the best strength and nutrition coaches to ask your questions and get the help you need. Best of all? The first month is risk free so you can ensure that the program is right for you.

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.
We have been in the health and fitness industry for almost 2 decades and have worked with many professional athletes as well as amateurs who used our products to help them perform at their best. We know how important it is to provide our customers with the best products on the market. We take great pride in our supplements and do not try to cut costs by using small dosages and fillers as many other companies do. When you purchase from us you can be absolutely confident you are getting the best quality and safest supplements you can find.
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