A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
The growing market has bred plenty of competition. A company called Now Foods is now making deer antler velvet lozenges. GNC just started selling deer antler velvet capsules called New Vigor from a company called Vitalast and Amazon.com has more than 30 products will deer antler velvet in it including the raw powder from New Zealand, where the most coveted deer velvet is harvested.
Dr. Low Dog also reports that a chronic wasting disease in deer, elk and moose is the only recognized prion (infectious protein) disease of wild animals and has been found in 15 states and two provinces in Canada. (Prion diseases in wild animals are similar to bovine spongiform encephalopathy, better known as mad cow disease, in cattle.) No known cases of neurological disease have been seen in humans who have taken deer antler velvet supplements, but a 2009 study sponsored by the National Institutes of Neurological Diseases and Stroke and the U.S. Department of Agriculture concluded that the possibility remains.
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Supplements are best used in situations where an individual is unable to get their nutrients from their diet. Perhaps an individual has an allergy or intolerance, for example lactose. They are unable to consume milk products which in turn limits their ability to get sufficient calcium and vitamin D from their diet. In that case, a supplement makes sense.

Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits.  It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels.  Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer.  Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.  
While consumers wanted more information on the product. Let’s not forget the supplement industry is a multi-billionaire dollar business. And if Ray used the product then it must be legit, right? That’s what the immediate response in supplement sales would have you believe, as ESPN business reporter Darren Rovel reported that purchases skyrocketed within 24 hours of the report.
IGF-1 can help slow this aging process down by increasing the telomere length of our DNA. Telomeres are a protective "cap" at the end of each strand of our DNA which prevents the DNA from becoming damaged. DNA becomes damaged as the telomeres grow shorter with age. As more DNA strands become damaged, cells in our bodies can no longer function properly which results in many medical conditions, diseases, and even death. This is how IGF-1 can help longevity. It does this by promoting healthy DNA strands to keep our cellular functions optimal.
In a study on diabetic mice given topical wounds (scalpel and scissors to create a cricle; diabetes tends to reduce wound healing rates[34] and thus diabetic rats are a good research model for wound closure rates) where either a control cream or one containing 400mcg Velvet Antler (Elk; water soluble extract) noted that there was less angiogenesis and a trend towards less inflammation assocaited with Velvet Antler cream while on day 7 wounds treated with the Antler cream were significantly smaller than control.[35] One 3.2kDa protein has been noted to possess wound healing properties, which are dose-dependent and have been noted to improve wound healing induced by burns at 0.05-0.1% of solution[36] and in vitro at 10-40mcg/mL.[37]

Some people use deer velvet to increase levels of certain sex hormones (estrogen and testosterone), improve fertility, increase interest in sexual activity (as an aphrodisiac), and treat male sexual performance problems (erectile dysfunction, ED). Women use deer velvet to reduce the dose of estrogen they need in hormone replacement therapy. They also use it for menstrual and menopause problems, vaginal discharges, and uterine bleeding.

Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 


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The word antler is derived from the Latin Anteoculae, meaning "in front of the eyes." Antlers are present in almost all members of the deer family Cervidae. The first documented evidence of deer velvet as a medicinal was found on a scroll recovered from a tomb in Hunan China dating back 2000 years. The use of antler dates back to the Han Dynasty 206 BC to 220 AD. A 16th century medical text, Pen Ts'ao Kang Mu, lists several antler preparations including pills, tinctures, and ointments. In traditional Chinese medicine, velvet antler has been used for over 2000 years as a tonic, to improve bone health, to nourish the blood, reduce swelling, and to treat impotence. Later research on deer antler dates back to the 1980s in Russia. Hundreds of articles have since been published including those documented by Chinese, Korean, and Japanese scientists.14, 15
Adaptogen: Adaptogens are natural metabolic regulators that increase a person’s ability to adapt to environmental factors-like pollution, smoke, stress, toxins etc. and to avoid damage from those factors. In other words, adaptogens literally help your body “adapt” to the environment without any side effects. If you’re living in the real world, with external or internal stressors, adaptogens help your body change in order to cope with the stressors.
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New Zealand research reports that although the mechanism is unknown, deer antler velvet shows strong anti-inflammatory effects. Recent clinical tests suggest oral ingestion of glycosaminoglycan-peptide complex, or components such as chondroitin sulfate and glucosamine sulfate — both found in deer antler velvet — may help stimulate cartilage repair.
Generally researchers agree that deer antler velvet protects, strengthens and restores the body's functions that are out of balance. In other words, it can act as an adaptogen on the human body, helping where it is needed. Studies suggest that deer antler velvet may have beneficial effects related to: increases in muscular development, strength and endurance; improved recovery; prevention and reduction of inflammation; improvement of sexual health; reduction in blood pressure; improvement in bone and joint health; stimulation of the immune system; and more.
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