In a double blind study (Edelman, 2000), 54 patients with arthritis in the knee were given deer antler velvet or a placebo and assessed at 1, 3 and 6 months. Patients treated with deer antler velvet showed improvement in pain and physical global assessment at 3 and 6 months. No significant improvement was observed for the placebo group for any of the parameters examined.
Being a former collegiate athlete, I’m no stranger to working out. When a former teammate of mine started talking about this new, state of the art, health product and the effects he was getting from it, it peaked my interest needless to say. I remember him continually saying that I’d have to try it to believe what it does for you. Wow, I must now say that I know what he means (and then some)! First of all, this IGF-1 Plus™ Formula did have some impressive results for me in my workouts. It’s not only helped my strength, but it seems that I especially notice a difference in my joints and my recovery time. Since I lift with heavy weights, my joints used to ache after working out, but they no longer do! My endurance also has really improved as well. I’ve actually doubled the time and distance that I was doing before (and I’ve only been on it for a little over a month)! An unexpected (but much welcomed) improvement that has been incredible is in how clearly I’ve been able to think and I feel very little stress anymore. It almost like someone put a micro-computer chip in my brain that makes it work much more efficiently without trying nearly as hard. It’s one of those things that you have to try to really believe it (trust me, it has done much more than I expected it to). I look forward to turning a friend of mine on to it, since he’s a personal trainer and trains professional athletes! Thanks, Dr. Duarte. I plan to use your IGF-1 Plus™ from now on, and will stock up so I don’t run out!
The FDA considers deer antler spray (or deer antler velvet) to be a dietary supplement. This means it doesn’t need to be extensively studied and regulated like medications. For this reason, it can be hard to tell what the actual concentration of active ingredients or IGF-1 is in various supplements. Plus products can differ quite a bit from one brand to another in terms of their purity and effectiveness.

According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.
Do not be fooled by companies who make false claims and be aware that there is a difference in deer antler velvet quality and absorption rate. Nutronics Labs only utilizes Grade A New Zealand Deer Antler Velvet extract in its various IGF liposome formulations. Nutronics Labs proprietary blend of Deer Antler Velvet extract in liposome formula carries the highest potency in the world and is free of any contaminants or filler compounds.
An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]

One study[14] (duplicated in Medline[15]) that used a water extract of Velvet Antler at 50-200mg/kg failed to inhibit the pain killing effect of Morphine yet reduced the rate at which rats became tolerant to Morphine over the course of 6 days when taken an hour prior to Morphine each day.[14] Rats who were given Velvet Antler prior to Morphine also experienced 26.6-36.6% less withdrawal (dose-dependent) and reduced reverse tolerance and dopamine receptor supersensitivity relative to morphine control.[14]
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Deer antler, or more specifically ‘velvet antler”which refers to the soft, newly grown antler before it hardens, not just the velvet skin’has been used in Chinese medicine for 2000 years. Often prescribed as a tonic, it is reputed to boost the immune system, improve stamina and reduce swelling. It is also prescribed to promote wound healing and strengthen bones and said to be an aphrodisiac and to enhance fertility. In China, velvet antler is seen as second only to ginseng in its restorative powers.
While consumers wanted more information on the product. Let’s not forget the supplement industry is a multi-billionaire dollar business. And if Ray used the product then it must be legit, right? That’s what the immediate response in supplement sales would have you believe, as ESPN business reporter Darren Rovel reported that purchases skyrocketed within 24 hours of the report.

Deer velvet might have an effect due to the hormones it may contain, including testosterone, androstenedione, and dehydroepiandrosterone. Research in rats, using elk velvet antler, suggested the substance may have an androgen-like effect. The antlers are ground into powder, which people take by mouth. Dosage varies by brand, but a recent study used 215 mg per day. Some distributers, though, recommend dosages ranging from 250 mg to as high as 3000 mg (3 g) per day. So talk with your doctor before you start using deer velvet.
Immortal Antler Velvet Silver is a less potent form of antler velvet than the Gold. It’s the only all-natural 19:1 extract that contains a powerful blend of growth factors in a naturally occurring matrix, and the only all-natural proprietary matrix to deliver up to 45 mcg’s of IGF-1 per bottle, in addition to the full growth factor matrix. Delivering a full range of growth factors at a 19:1 ratio means it requires 19 lbs of velvet antler tips to create 1 lb of this complete formula. Immortal Antler Velvet Silver is extracted in organic grape alcohol and bottled in miron violet glass for maximum absorption and effectiveness.
This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.
To be clear, some doctors and researchers have stated that they feel deer antler spray is unlikely to cause any significant benefits. This is because it only provides very small amounts of IGF-1, some of which may not even be fully absorbed. However, studies do show that higher doses, or using very high-quality supplements, may contribute to some improvements in performance, body composition, etc. IGF-1 itself has been studied extensively. It can certainly change the way the body looks and operates. Whether or not the role of IGF-1 in the body will translate into any real benefits when obtained from deer antler products will depend on the specific person and dosage used.
Powdered velvet antler is available in capsule form from health shops. As a general tonic and to fight fatigue, the recommended dosage is usually 1 or 2 capsules (250 to 350 milligrams each) per day. For conditions such as osteoarthritis, higher doses may be used under supervision of a health practitioner. The effects of velvet antler gradually accumulate and are typically seen 8 to 12 weeks.
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Deer antler velvet has made its way into the spotlight recently thanks to claims that Super Bowl winner Ray Lewis used it in spray form to recover from his October triceps injury. Lewis denied the claim, but had many people wondering if deer antler velvet, a substance that is banned by the NFL and claims to increase strength and boost muscle recovery, really works. The natural supplement, made from the fuzz that covers male deer antlers, is a growth hormone known as IGF-1, which supposedly can repair cartilege damage and increase strength and muscle mass. 
On January 30, 2013, Vijay Singh professional PGA Tour golfer was caught unaware and openly admitted to the personal use of deer antler spray which contained a banned substance at the time.[22] A week later the World Anti-Doping Agency (WADA) lifted the ban on deer antler spray, but with urgency, "Deer Antler Velvet Spray may contain IGF-1 and WADA recommends therefore that athletes be extremely vigilant with this supplement because it could lead to a positive test." [23] The consensus opinion of leading endocrinologists concerning any purported claims and benefits "is simply that there is far too little of the substance in even the purest forms of the spray to make any difference," [9] and "there is no medically valid way to deliver IGF-1 orally or in a spray." [24]
The word antler is derived from the Latin Anteoculae, meaning "in front of the eyes." Antlers are present in almost all members of the deer family Cervidae. The first documented evidence of deer velvet as a medicinal was found on a scroll recovered from a tomb in Hunan China dating back 2000 years. The use of antler dates back to the Han Dynasty 206 BC to 220 AD. A 16th century medical text, Pen Ts'ao Kang Mu, lists several antler preparations including pills, tinctures, and ointments. In traditional Chinese medicine, velvet antler has been used for over 2000 years as a tonic, to improve bone health, to nourish the blood, reduce swelling, and to treat impotence. Later research on deer antler dates back to the 1980s in Russia. Hundreds of articles have since been published including those documented by Chinese, Korean, and Japanese scientists.14, 15
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
In Russia, Korea and China, deer antler velvet is widely used by athletes to enhance performance. In the United States, more and more athletes are looking to deer antler velvet as a training aid, a promoter of recovery after physical activity and injury, and possibly an injury preventative. Deer velvet could improve athletic performance in many ways, for example by assisting strength and endurance, by supporting the oxygen-carrying capacity of the blood, by facilitating minor tissue damage, and by boosting the immune system.
Deer antler velvet is used for its purported ability to raise testosterone levels to treat decreased libido (low sex drive), infertility, and erectile dysfunction in men.  It is used in combination with other herbs to treat sexual dysfunction and hormonal dysfunction in men and women.  It is used to treat conditions resulting from deficient kidneys.  Some people use it because of its reputed benefit as an aphrodisiac and muscle strength enhancer.  It is also sometimes prescribed to help alleviate withdrawal symptoms in the treatment of morphine addiction.  
As you know I’ve been a Hollywood stuntman and director for over 30 years and during my stunt man career I have accumulated many injuries along with aches, pains and arthritis. Since I’ve been taking your IGF-1 product, my arthritis is 100% better and I’ve forgotten about my injuries. This product is truly amazing and has worked wonders for me. I also appreciate the sleep miracle as it helps me get a good nights sleep and feel great in the morning.
IGF-1 is currently on the World Anti-Doping Agency’s prohibited list due to how it gives athletes an unfair advantage in terms of building strength and muscle mass. (7) However, it’s still legal to use supplements that may provide IGF-1 or similar effects. Most of the studies that show positive results from using deer antler supplements have used high doses. And some have tested the product on animals (mice or rats) rather than humans.
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