Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.

One double-blind study published in the International Journal of Sports Nutrition and Exercise Metabolism tested whether or not deer antler velvet powder or extract had an impact on aerobic performance, endurance and “trainability of muscular strength” compared to a placebo. The subjects were adult males. They were given either a placebo, or deer antler extract or powder supplementation over a  10-week period while undergoing a strength-building routine. The men were measured for muscular strength, endurance, and VO2max before and after using deer antler. These results were determined by measuring circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume.
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A study by Chen found that deer antler velvet inhibits monoamine oxidase activity in the liver and brain tissues of aged mice. Monoamine-oxidase inhibitors prevent breakdown of monoamine neurotransmitters such as norepinephrine and serotonin. Antler apparently allows these vital neurotransmitters to be available longer to the brain structure, enhancing mood.
No direct reports of chronic wasting disease (CWD) related to deer velvet supplementation have been published. However, several Web sites contain disclaimers mentioning the possibility of the disease being present in antler products. The CDC has not yet found a relationship between CWD and any neurological disease that affects humans with deer velvet use.

Generally researchers agree that deer antler velvet protects, strengthens and restores the body's functions that are out of balance. In other words, it can act as an adaptogen on the human body, helping where it is needed. Studies suggest that deer antler velvet may have beneficial effects related to: increases in muscular development, strength and endurance; improved recovery; prevention and reduction of inflammation; improvement of sexual health; reduction in blood pressure; improvement in bone and joint health; stimulation of the immune system; and more.
Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes.[18] In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars.[19][20] In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." [21]
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According to modern research, deer antler velvet has shown gonadotropic activity. Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging. The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone.

Tribulus: An extract taken from the Mediterranean puncture vine that some cultures believe to have medicinal values. There is little clinical data surrounding the bio-physical effects of tribulus, however some people take it to enhance athletic performance, sexual ability, and improve circulation. Not much is known about the long-term consequences of tribulus consumption, however there are some indications that it may potentially lead to prostate issues in some men.
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A growing trend in western medicine is the proliferation of influences from ancient eastern medicine. Over 2,000 years ago, the Chinese were administering deer antler velvet to treat conditions ranging from serious illnesses to lack of sexual desire. After closely examining the wide range of health benefits deer antler velvet promotes, it's no wonder why the Chinese used it as a medicine for thousands of years.

In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 
Deer antlers have been closely linked to IGF-1, which is another term for insulin. This has been well received in eastern medicine as an anti-aging and bodybuilding product. Because it’s also a known natural growth hormone, it’s said to aid in muscle development by enhancing strength and improving recovery time. This is what attracts bodybuilders to this product.
Deer antler spray — a supplement commonly used in the fitness and sports industries that has a long history of use in Eastern medicine — is pretty much as strange as it sounds. Derived from the tissue found inside deer antlers, it’s reported to work by providing IGF-1 (insulin-like growth factor), a natural growth hormone found inside the human body that has potential to increase muscle mass and support recovery from injuries.
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Deer velvet might have an effect due to the hormones it may contain, including testosterone, androstenedione, and dehydroepiandrosterone. Research in rats, using elk velvet antler, suggested the substance may have an androgen-like effect. The antlers are ground into powder, which people take by mouth. Dosage varies by brand, but a recent study used 215 mg per day. Some distributers, though, recommend dosages ranging from 250 mg to as high as 3000 mg (3 g) per day. So talk with your doctor before you start using deer velvet.
In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]
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But when it comes to sprays or pills, there’s little evidence that deer antler offers performance enhancing benefits of any kind, says Alan Rogol, M.D., an endocrinologist at the University of Virginia. Rogol is also part of a small team of doctors that assists anti-doping agencies in determining if and when athletes can use certain controversial substances.
These are required in enzyme and catalytic cellular functions as well as being the raw material for tissues. Growth factors are known to boost cellular functioning and uptake of nutrients This helps our own growth, regeneration of tissues and injury recovery, as well as a slowing and preventing the effects of agings. Many hormones are closely associated with IGF-1
I took red mountain deer velvet and it really messed my stomach up. I now have cramps and bloating all the time plus it feels like my stomach shrank…I can’t eat like I used to. It was a big mistake to take that stuff. Do you know of any way I can get my stomach back to normal??? Can you recommend someone who knows a lot about deer velvet?? I have been suffering terribly since I took that junk…it’s been about 2 years now!!!! My stomach has never been the same since I took that poison!!
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