On to the Deer Antler Spray and it’s positive effects this has had on my wife and I. Starting with me: In 2005 I had a titanium cage put into my L4-L5 lumbar region. My left leg was always numb and slept very little until a great neurosurgeon repaired it. Then 1 day I was on my 2 mile walk, and all of a sudden I felt this horrible left side pain. By that night my son, who was 16 at the time, said that my left side was all swelled up. It was hell all over again for me. I went to many doctors, stopped many in the halls of the University of Iowa Hospitals and asked if they could give me a tell. Of course none of them knew either. I was on hydrocodone for 4 years and also put on Lyrica. After hearing about Ray Lewis making this remarkable comeback from his tricep injury, which was really damaged and at his age should have retired, he came back for the playoffs. This blew me away because I also know much about sports injuries being I am an ex-athlete.
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Deer antler velvet has been used in China for over 2,000 years. More recently, Soviet scientists in the 1980s tested the effects of deer antler velvet on the performance of elite Russian athletes, and the results were astonishing. Deer antler velvet helped increase the strength and muscle mass of Russian athletes, and speed their recovery time from exercise.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.