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But when it comes to sprays or pills, there’s little evidence that deer antler offers performance enhancing benefits of any kind, says Alan Rogol, M.D., an endocrinologist at the University of Virginia. Rogol is also part of a small team of doctors that assists anti-doping agencies in determining if and when athletes can use certain controversial substances.

One study[14] (duplicated in Medline[15]) that used a water extract of Velvet Antler at 50-200mg/kg failed to inhibit the pain killing effect of Morphine yet reduced the rate at which rats became tolerant to Morphine over the course of 6 days when taken an hour prior to Morphine each day.[14] Rats who were given Velvet Antler prior to Morphine also experienced 26.6-36.6% less withdrawal (dose-dependent) and reduced reverse tolerance and dopamine receptor supersensitivity relative to morphine control.[14]


Velvet antler has been used in traditional Chinese medicine (TCM) that classifies many similar substances from a variety of species under the simplified Chinese name 鹿茸; (pinyin Lu Rong) and the commercial name Cervi Cornu Pantorichum.[citation needed] The two common species used within the TCM system are sika deer and red deer which are thought to be useful for treating yang deficiency syndromes.[6][7][8]
There is some evidence that deer antler spray may work for improving performance and physique. However, it seems that an individual needs to take very high doses in order for these benefits to occur. In studies where the supplement was effective, injections of very concentrated extracts were used. Injections may be the most effective, and likely the only, way that deer antler works. This is because IGF-1 is mostly destroyed when it passes through the digestive system. Because of this, swallowing deer antler supplements would practically be useless.
Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits.  It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels.  Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer.  Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.  
Deer antler velvet is the tissue that covers the bone and cartilage that develop into deer (and elk) antlers. It has been harvested for centuries and used traditionally to increase strength, boost the immune system, and counter the effects of stress. Now it’s promoted to improve athletic performance; raise testosterone levels to increase sex drive, fertility and erectile function in men; as well as to reduce the signs of aging and treat problems ranging from high cholesterol, high blood pressure, asthma and osteoporosis to migraine headaches, indigestion, and many more.
(Adult) Shake well before each use. As a dietary supplement, spray 3 to 5 times under tongue as needed. Hold for 20 seconds before swallowing for best results. Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication. *Contains Soy
Moose, elk and deer produce new antlers yearly (primarily males, except in caribou/reindeer). In New Zealand, deer are subject to local anesthesia and restrained during antler removal, and the procedure is supervised by licensed veterinarians.[3][4] Typically, the antler is cut off near the base after it is about two-thirds of its potential full size, between 55 and 65 days of growth, before any significant calcification occurs.[4] The procedure is generally done around June in the Northern Hemisphere and December in the Southern Hemisphere.[5]
The company has found that powders have only about a 15–20 percent absorption rate of IGF-1. This is due to how the digestive system breaks down the powder. Nutronics states that their “proprietary sublingual spray delivery system” is superior to many competitors because it offers “enhanced bioavailability” of IGF-1. They also point out that “it is not the milligrams of Deer Antler Velvet in the product, it’s the content of IGF-1 and other Growth Factors in Deer Antler Velvet, that makes the difference.”(6)
Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Many conditions lead to joint pain from aging to an untreated sports injury. A quality joint product may help repair existing tissue damage and also promote stronger joints, less susceptible to future degeneration.

Sourced from New Zealand, Piping Rock’s IGF-1+ extra strength Deer Antler Velvet Spray taps into ancient practices famously exploring male virility.** Each spray contains the beneficial amino acids, peptides, proteins and insulin-like growth factor-1 (IGF-1+) naturally found in deer velvet, making this spray a popular choice among athletes, fitness enthusiasts and those who are looking to support muscle strength, stamina, vitality and overall male performance.**

Blood Pressure: Almost 30% of Americans (28.7%) have high blood pressure. If you’re 60 years of age, 65.4% of your age group has it. If you’re black, 33.5% vs. 28.7% of whites, have high blood pressure. It’s a very common problem-and only gets worse as we age. So why should you worry about your blood pressure? Because high blood pressure is the cause of heart attacks, stroke, blindness, kidney disease and failure and death to name a few reasons. Did you know that 5 million people in US have high blood pressure, including those getting treated for it? But wait-almost 40 million people don’t know they have it, aren’t getting it treated or can’t control it adequately! Are you one of them? Ask your doctor. Deer Antler Velvet has been shown to reduce high blood pressure naturally, without side effects and without interfering with any medication you’re already on.
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization.  In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to.  (That’s not a value judgment, just the facts.)
Deer antler velvet can act as a natural adaptogen, restoring homeostasis to an unbalanced body by helping where it is needed. Deer antler velvet has an effect on many systems of the body given its complex chemical composition. The active ingredients in deer antler velvet are mostly precursors that are required by the body to process substances that maintain its health and wellbeing.
In what might be the most important study done in the United States, a group of scientists took 32 male weight lifters and gave half of them New Zealand Deer Antler Velvet and half of them a placebo for 10 weeks. While the placebo group didn't show any difference in bench or squat tests, those given deer antler velvet saw an increase of 4 percent on the bench press and 10.1 percent on the squat test as compared to the placebo group. The scientists also reported that there was a "significant improvement in aerobic capacity" with the group that was taking deer antler velvet.
A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
Nutronics Labs Stress Relief Plus will help alleviate Anxiety, Panic Attacks, PTSD and every day Stress within minutes of administering this unique product, with it’s proprietary blend of Valerian Root extract, Passion Flower Root extract, 5-HTP from Griffonia Seed extract, and Deer Antler Velvet extract (containing IGF-1 and other various health promoting elements). STRESS RELIEF PLUS IS NOT ADDICTIVE! Rest assured, with Nutronics Labs liposome spray delivery system, you will always be receiving Maximum Benefits with our enhanced bioavailability! By spraying Stress Relief Plus under your tongue, holding it there for about 20 seconds before swallowing, typically within minutes you’ll be enjoying the soothing effects. With our compact bottle, it is convenient to carry with you wherever you are or wherever you are going. So you can relax and experience the calming effects of Nutronics Labs Stress Relief Plus!
In September, 2013, the headquarters of S.W.A.T.S. was raided and ordered to be shut down by Alabama's attorney general citing "numerous serious and willful violations of Alabama’s deceptive trade practices act".[30][31] Among the violations were "claims that the company made about a number of products that were unsupported by scientific research. Some of these products were marketed as 'dietary supplements.'" [32] The assistant Alabama attorney general "says that Deer Antler Spray is dangerous and its sellers are law-breakers." [33]

Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves,[31][32] although testosterone may be the primary growth factor.[33] Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.[26]
Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 
In the days leading up to Super Bowl XLVII we’ve heard a lot about deer antler velvet and the question of whether or not Baltimore Ravens’ linebacker Ray Lewis used an extract of it (in spray form) to help heal the triceps muscle he tore in October 2012. This could be a problem for Lewis, since deer antler velvet contains a substance that is banned by the National Football League (NFL).

World harvest extends far and wide. The farming of deer species for their velvet antler has been occurring for a long time in China and Russia. The Asian industry raises a predominant amount of sika, aka. spotted deer, on private and communal farms where they are well cared for by private owners. Quality of a this profound botanical is of utmost importance. Farms in Asia it is also both industry and government regulated for quality, safety, and the welfare of the animals.


For a long time velvet antler is recognized as a powerful tonic that naturally stimulates us with a clean and non-fatiguing energy. Not like coffee or energy drinks. This effect can be subtle, but its long term consumption benefits are profound in that we can more easily overcome and adapt to daily stress. Many types of stress depending on who we are as individuals. How much to take is important and talked about in the dosage section. Having the capability of increased resistance to physical stress is a major use to everyone. 

A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.


Tissue Growth* - Ancient use was as a growth tonic for underdeveloping children and as a gland activator for the glandularly deficient.* It was also recommended to maturing people because of this interesting action on the body.* In modern times it has been discovered that very small amounts of key constituents, called growth factors, signal cellular structures for regeneration and growth, and are found in deer antler velvet extract itself and in larger amounts within the circulating blood of those who take it.*
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.

(Adult) Shake well before each use. As a dietary supplement, spray 3 to 5 times under tongue as needed. Hold for 20 seconds before swallowing for best results. Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication. *Contains Soy


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with cardio and strength. Keep in mind I was active my whole life and fairly strong for my size and age. My endurance was crazy and I often out worked guys 18-40 without thinking twice. Since the injury I have more pain and less endurance. I never slept good but since the injury “night time” sleep is horrible at times. up for over 24hrs. Though I am not great the next day I still functioned can work a full day. IN general I sometimes fatigue and have to nap after a workout -which is a pathetic workout compared to the workouts I used to do.
To determine the effects of deer antler velvet on maximal aerobic performance and the trainability of muscular strength and endurance, 38 active males were randomly assigned in a double-blind fashion to either deer antler velvet extract (n = 12), powder (n = 13), or placebo groups (n = 13). Subjects were tested prior to beginning supplementation and a 10-week strength program, and immediately post-training. All subjects were measured for circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume. Additionally, muscular strength, endurance, and VO2max were determined. All groups improved 6 RM strength equivalently (41 +/- 26%, p < .001), but there was a greater increase in isokinetic knee extensor strength (30 +/- 21% vs. 13 +/- 15%, p = .04) and endurance (21 +/- 19% vs. 7 +/- 12%, p = .02) in the powder compared to placebo group. There were no endocrine, red cell mass or VO2max changes in any group. These findings do not support an erythropoetic or aerobic ergogenic effect of deer antler velvet. Further, the inconsistent findings regarding the effects of deer antler velvet powder supplementation on the development of strength suggests that further work is required to test the robustness of the observation that this supplement enhances the strength training response and to ensure this observation is not a type I error.
People with osteoarthritis take chondroitin sulphate as an anti-inflammatory and velvet antler contains a high concentration of this compound, as well as significant amounts of glucosamine sulphate. Both appear to inhibit the depletion of bone and cartilage. The use of velvet antler in treating rheumatoid arthritis is being studied at the University of Calgary and the University of Alberta.
In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
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