An ethanolic extract has been noted to, following oral ingestion of 100mg/kg, suppress nitric oxide secretion from peritoneal macrophages while stimulating phagocytic activity secondary to calcium mobilization,[19] and has been noted to increase macrophage cell count in a concentration dependent manner up to 171.5% at 150mcg/mL with a water extract (and 132.4% for splenocytes).[18] This immunostimulation appears to be related to phosphatidylcholine molecules with saturated fatty acid acyl chains[20] and is thought to underlie an anti-infective effect in mice infected with Staphylococcus aureus when Velvet Antler is ingested at 500mg/kg.[18]
Deer Antler Velvet Spray has been tested and results show that this is safe. It doesn’t contain the controversial Human Growth Hormone, but it offers the same benefits. This doesn’t need a prescription. However, the site states that some have experienced mild stomach pains. While this is considered a supplement, doctors still advise you to go in for consultation because this product is surrounded with controversy and isn’t well accepted by the medical community.
There is an increasing amount of scientific evidence supporting the benefits of deer antler velvet from decades of research carried out in Russia, Korea, China, Japan, Australia and New Zealand. This research has given credibility to deer antler velvet’s traditional usage and validated recommendations for its inclusion as an everyday health supplement. Almost 250 papers have been published since 1930 on the manufacture, composition and biochemical effect of deer antler velvet. Studies on deer antler velvet and the corresponding findings are described below.
Other studies reported an increase in heart strength and volume of blood pumped, while cardiac output, heart rate, mean arterial pressure, pulse pressure, central venous pressure and other parameters remained unchanged. Researchers suggest that the polysaccharides in antler may reduce the blood’s tendency to clot, improving circulation, decreasing stroke risk and boosting general cardiovascular health. Researchers theorize that the deer antler velvet may improve blood supply to muscles or act as an anti-inflammatory, allowing athletes to recover faster from training sessions.
More recent tests (Slievert, 2003) confirm deer antler velvet’s effects on muscle strength and endurance. In a randomized, double blind, placebo controlled experiment, 18 males entered a 10 week strength training program. Those who took deer antler velvet showed an increase in maximal aerobic capacity, an increase in strength in the bench press and leg squat, and decrease in body fat relative to the placebo group.
First, the following disclaimer: Products that are sold as supplements (as opposed to medications) are not regulated by the Food and Drug Administration so they are not tested for safety, efficacy or standardization.  In other words, when you buy a supplement, there is no guarantee that what is in the bottle has been tested to see if it even contains the ingredient in question, let alone whether the ingredient actually does what it claims to.  (That’s not a value judgment, just the facts.)
I was first introduced to and started using IGF-1 Plus™ in July of 1999. I made it part of my daily regiment originally to increase my stamina and build my muscles while burning body fat at the same time (which I was informed this would help me accomplish). I am 35 years old and exercise for about an hour or so at a time, 3 to 4 times a week. It is now the end of February 2000 and I’m extremely impressed at the results! People have commented on my appearance and I have been reaching new heights in the gym that I though were only obtainable by using drugs like steroids (which I never considered taking due to the unwanted side effects). However IGF-1 has not only increased my strength and endurance, but has given me much more in ways that I had not anticipated! For instance, the person who shared this with me had no idea that I have arthritis. I would wake up in the morning and my joints would ache severely (especially my wrists and elbows) until eleven o’clock or noon. Now, although it took me a few weeks to start really noticing my improvements in the gym, it didn’t take but 3 -4 days for me to take notice of the fact that my morning arthritis pains were completely gone. The only time the pain has come back is when I ran out of the spray and couldn’t get a hold of any for a couple of weeks because I was out of town vacationing in Florida. Now I try to have at least a couple extra bottles on hand! Also, my hair stylist of 17 years had noticed that I had lost a significant amount of gray on my head and asked if I was coloring my hair. I’ll make sure I never run out of this amazing formula again!!!
Deer Antler Velvet Spray has been tested and results show that this is safe. It doesn’t contain the controversial Human Growth Hormone, but it offers the same benefits. This doesn’t need a prescription. However, the site states that some have experienced mild stomach pains. While this is considered a supplement, doctors still advise you to go in for consultation because this product is surrounded with controversy and isn’t well accepted by the medical community.
A friend of mine gave me a bottle of your product about a month ago and I started taking it and, within a week, I started to feel energized at all hours of the day. In addition, as an actor I noticed an improvement in my memory. Most recently, I have seen a dramatic re-shaping of my body. I am gaining muscle mass and I have not trained or worked out in months! As a avid body builder most of my life, I noticed increased muscle mass without exercising, fat loss without dieting, higher energy levels, lower blood pressure, lower LDL cholesterol, younger and thicker skin, hair re-growth, wrinkles disappearing, sharper vision and bearing and of course increased memory retention…

For a long time velvet antler is recognized as a powerful tonic that naturally stimulates us with a clean and non-fatiguing energy. Not like coffee or energy drinks. This effect can be subtle, but its long term consumption benefits are profound in that we can more easily overcome and adapt to daily stress. Many types of stress depending on who we are as individuals. How much to take is important and talked about in the dosage section. Having the capability of increased resistance to physical stress is a major use to everyone. 
The truth? While research is limited, there’s nothing to suggest that deer antler velvet (or deer antler spray in the supplement form) actually does what it claims. In fact, there are two published studies (in real scientific journals, you can see them here and here) that suggest deer antler velvet does not (I repeat, does not) even elicit a hormonal response. What’s more, it also did not increase muscular strength or aerobic power.
World harvest extends far and wide. The farming of deer species for their velvet antler has been occurring for a long time in China and Russia. The Asian industry raises a predominant amount of sika, aka. spotted deer, on private and communal farms where they are well cared for by private owners. Quality of a this profound botanical is of utmost importance. Farms in Asia it is also both industry and government regulated for quality, safety, and the welfare of the animals.
My name is William Gucciardo. I am fifty-four years old and have been exercising and taking nutritional supplementation for many years. I was recently introduced to IGF-1, and have been taking it for three weeks. Although I have been working out six days a week for the past several years, I have recently noticed an increase in upper body muscle tone and overall strength and endurance. I have also noticed that minor stiffness that I daily experienced upon arising in the morning is gone. My body feels stronger with an overall feeling of well being. I can only attribute these changes to the addition of IGF-1 to my supplementation program, as this is the only change that I have recently made. I do not know what further benefits I will receive from taking IGF-1 daily. If you are willing to try something new with the possibility of improving your health and well being, I would recommend trying this product.
In rats undergoing left coronary artery ligation, those with heart failure were given either Velvet Antler (Deer) or Captopril as active control for 4 weeks with a third group given water.[17] No significant changes in cardiac structure was noted with either Velvet Antlers or Captopril (with the heart tissue being enlarged after heart failure) although left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) appeared to be improved in both treatment groups to approximately the same degree and the increase in serum Brain Natiuretic Peptide (BNP) that occurred with heart failure was attenuated the same degree in both interventions.[17]
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.
Deer antler velvet can act as a natural adaptogen, restoring homeostasis to an unbalanced body by helping where it is needed. Deer antler velvet has an effect on many systems of the body given its complex chemical composition. The active ingredients in deer antler velvet are mostly precursors that are required by the body to process substances that maintain its health and wellbeing.
A study by Chen found that deer antler velvet inhibits monoamine oxidase activity in the liver and brain tissues of aged mice. Monoamine-oxidase inhibitors prevent breakdown of monoamine neurotransmitters such as norepinephrine and serotonin. Antler apparently allows these vital neurotransmitters to be available longer to the brain structure, enhancing mood.

A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.