One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed.[26] The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.[27]
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Moose, elk and deer produce new antlers yearly (primarily males, except in caribou/reindeer). In New Zealand, deer are subject to local anesthesia and restrained during antler removal, and the procedure is supervised by licensed veterinarians.[3][4] Typically, the antler is cut off near the base after it is about two-thirds of its potential full size, between 55 and 65 days of growth, before any significant calcification occurs.[4] The procedure is generally done around June in the Northern Hemisphere and December in the Southern Hemisphere.[5]

One double-blind study published in the International Journal of Sports Nutrition and Exercise Metabolism tested whether or not deer antler velvet powder or extract had an impact on aerobic performance, endurance and “trainability of muscular strength” compared to a placebo. The subjects were adult males. They were given either a placebo, or deer antler extract or powder supplementation over a  10-week period while undergoing a strength-building routine. The men were measured for muscular strength, endurance, and VO2max before and after using deer antler. These results were determined by measuring circulating levels of testosterone, insulin-like growth factor, erythropoietin, red cell mass, plasma volume, and total blood volume.
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Velvet Antler is a supplement derived from powdered or crushed antlers, most commonly from deer (and thus referred to as Deer Velvet Antler) although Elk have also been used. They have been used in Traditional Chinese Medicine.[1] The base of the antler is referred to as Cervus (in reference to deers), Lu Jiao Pan, Zhen Zhu Pan, as well as Lu Hua Pan and appears to have been traditionally used for cardiovascular disease, gynecological problems, immunological deficiencies, blood cancers, tissue repair and health promotion.[1] The specific part used is the antler base; when the antler is sawed off the base temporarily remains until the regeneration of the new antler pushes it off which occurrs occasionally in the wild. Traditional usage involves using the base and macerating it in wine or decocting it with water for oral consumption.[1]
In herbal combinations, deer velvet is used to improve athletic performance; to improve eyesight and hearing; to reduce stress; and to treat arthritis, osteoporosis, “tired blood” (anemia), women’s reproductive disorders including premenstrual syndrome (PMS), ED, and skin conditions. Herbal combinations including deer velvet are also used to increase blood circulation to the brain and to delay or reduce signs of aging such as tissue, bone, and muscle degeneration, and declining mental skills.
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In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 
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