Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves,[31][32] although testosterone may be the primary growth factor.[33] Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.[26]
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Deer velvet might have an effect due to the hormones it may contain, including testosterone, androstenedione, and dehydroepiandrosterone. Research in rats, using elk velvet antler, suggested the substance may have an androgen-like effect. The antlers are ground into powder, which people take by mouth. Dosage varies by brand, but a recent study used 215 mg per day. Some distributers, though, recommend dosages ranging from 250 mg to as high as 3000 mg (3 g) per day. So talk with your doctor before you start using deer velvet.
People with osteoarthritis take chondroitin sulphate as an anti-inflammatory and velvet antler contains a high concentration of this compound, as well as significant amounts of glucosamine sulphate. Both appear to inhibit the depletion of bone and cartilage. The use of velvet antler in treating rheumatoid arthritis is being studied at the University of Calgary and the University of Alberta.
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with cardio and strength. Keep in mind I was active my whole life and fairly strong for my size and age. My endurance was crazy and I often out worked guys 18-40 without thinking twice. Since the injury I have more pain and less endurance. I never slept good but since the injury “night time” sleep is horrible at times. up for over 24hrs. Though I am not great the next day I still functioned can work a full day. IN general I sometimes fatigue and have to nap after a workout -which is a pathetic workout compared to the workouts I used to do.

I know of no scientific evidence to support any of the marketing claims made for these supplements. I discussed your question with Tieraona Low Dog, M.D., an internationally recognized expert in the fields of integrative medicine, dietary supplements and women’s health, and an authority on botanical medicine. She explains that IGF-1 in the velvet promotes rapid growth of the antler. Dr. Low Dog notes that the two studies examining the effects of deer antler velvet supplements taken by athletes have yielded conflicting results. One showed some improvements in endurance and knee strength in weightlifters, but the other found no differences in rowers after 10 weeks of supplementation.

A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.

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