More recent tests (Slievert, 2003) confirm deer antler velvet’s effects on muscle strength and endurance. In a randomized, double blind, placebo controlled experiment, 18 males entered a 10 week strength training program. Those who took deer antler velvet showed an increase in maximal aerobic capacity, an increase in strength in the bench press and leg squat, and decrease in body fat relative to the placebo group.
Velvet antler in the form of deer antler spray has been at the center of multiple controversies with professional sports leagues and famous athletes allegedly using it for injury recovery and performance enhancement purposes. In mid-2011 a National Football League (NFL) player successfully sued a deer antler velvet spray manufacturer for testing positive for methyltestosterone in 2009 for a total amount of 5.4 million US dollars. In August 2011, Major League Baseball (MLB) added deer antler spray to their list of prohibited items because it contains "potentially contaminated nutritional supplements." 
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A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.