However, calcium and phosphorus levels (which are important for bone growth) did not differ among groups. Overall, the researchers concluded that “our results seem to support a role for dietary supplementation of EVA on growth and bone development in this model.” (9) However, it’s important to point out that this is a very high dose. It’s significantly above what most would take in supplement form.
All male members of the deer family, including elk, moose and reindeer (caribou), grow a new set of antlers each year’from scratch, in just a matter of months’then shed them at the end of the annual mating season. The ability to regenerate such large appendages each year is unique to this family among mammals and rare in the animal kingdom as a whole (horns, in contrast to antlers, are permanent and cannot be regrown). Understanding how it happens could have significant implications for human medicine, particularly in the fields of wound healing and organ regeneration.
A Russian study indicated that the amino acids, polypeptides and other compounds found in antler increased the survival rate of mice with cancerous tumors as much as 40 percent. In addition, a study conducted by the East-West Research Institute in Korea found that deer antler velvet appears to increase neutrophil levels in mice, which boost the body’s ability to fight injuries and disease. The mice with tumors lost less weight and suffered lower levels of kidney damage than those treated with drugs.
In another randomized, double blind, placebo controlled experiment (Broeder, 2004), 38 males, all of whom were experienced weightlifters, entered a 10 week strength training program. Those who took deer antler velvet experienced an increase in peak torque and average power relative to the placebo group. They also experienced unexpected improvements in aerobic performance.
Generally researchers agree that deer antler velvet protects, strengthens and restores the body's functions that are out of balance. In other words, it can act as an adaptogen on the human body, helping where it is needed. Studies suggest that deer antler velvet may have beneficial effects related to: increases in muscular development, strength and endurance; improved recovery; prevention and reduction of inflammation; improvement of sexual health; reduction in blood pressure; improvement in bone and joint health; stimulation of the immune system; and more.
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This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.
One study published in the Journal of Ethnopharmacology found evidence that use of deer velvet antler may help strengthen joints and bones, reducing symptoms like joint pain associated with osteoarthritis. (10) After rats with osteoarthritic symptoms were given total velvet antler polypeptides from red deer (TVAPL) for 12 weeks, they showed signs of significant reversal in osteoporosis. The researchers found improvements in the rats’ bone weight coefficient (BWC), bone mineral density (BMD), and bone mineral content (BMC). They believe these effects were due to proliferation of cartilage and osteoblast-like cells, in addition to reductions in inflammation due to inhibition of interleukin-1 (IL-1).
Even more intriguing is how the stags manage to regrow their antlers. Scientists have found stem cells at the bases of antlers’essentially ‘blank’ cells that can develop into many different types of cell, such as a skin cell or a cartilage cell. If they could find out what triggers the stem cells and controls their development into antlers, the knowledge could be applied to the regeneration of human limbs and organs. Scientists know that the shedding is initiated by a fall in the hormone testosterone, a change linked to an increase in day length, and they think oestrogen may be a key cellular regulator. However, much more research on a molecular level is required to unravel what is clearly an intricate process.
In the days leading up to Super Bowl XLVII we’ve heard a lot about deer antler velvet and the question of whether or not Baltimore Ravens’ linebacker Ray Lewis used an extract of it (in spray form) to help heal the triceps muscle he tore in October 2012. This could be a problem for Lewis, since deer antler velvet contains a substance that is banned by the National Football League (NFL).
Deer antlers are the only mammalian bone structures to regenerate completely every year.1 Deer antler velvet is the epidermis covering the inner structure of the growing bone and cartilage, which develops into antlers.2 This tissue grows each spring on male Cervus sp. (North American elk and red deer) and should be removed by a veterinarian or certified farmer. The ethics, including use of local anesthetics, and procedures of harvesting antler velvet have been reported.3, 4, 5, 6 Velvet yield depends on several factors, including season, parasites, or injury.7 After removal of the deer velvet, it is collected and then frozen or dried prior to its manufacture into various "medicinal" forms including powders, extracts, teas, capsules, and tablets. Each part of elk velvet contains varying compounds, but the deer antler velvet contains the largest concentrations of those found to be beneficial. (Antler also has been sold by the slice). Heating during processing may reduce or destroy the purported beneficial effects of velvet antler. Various preparation methods, including freeze-drying and non-heat-producing methods have been reported.8, 9, 10, 11, 12, 13
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Shake well before use. As a dietary supplement, spray 2 times under tongue, 3 times per day. Hold the liquid under your tongue without swallowing for 20 seconds. This allows the formula to penetrate through your endocrine glands. Then the active molecules are then released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability! Caution: Do not use if outer seal is broken. Not intended for individuals under the age of 18. Consult your health care provider prior to use if you are pregnant or nursing, have a medical condition, or when taking any medication.
Research in Korea, New Zealand and China has shown that deer antler velvet can stimulate the immune system. Extracts of deer antler velvet were variously shown to increase macrophage activity, stimulate the production of lymphocytes and increase the number of red and white blood cells. Each of these effects may directly complement the body’s ability to resist or fight disease and so promote and maintain health and an associated feeling of well being.
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Repeated studies have been conducted on the interactions of Velvet Antler and hormones, and all studies have found that this supplement has failed to increase circulating hormone levels. One study found a highly variable increase in power output, which is antagonized by another study suggesting no significant increase in power. For the purposes of performance enhancement, the evidence does not currently support Velvet Antler as a supplement.
The harvesting of deer antler velvet can be a painful process, as the velvet tissue contains an abundance of nerves and bleeds profusely if cut or removed. Dr. Low Dog says she has no problem with harvesting velvet from deer killed for food, but is concerned that shortcuts will be taken should demand for the supplements continue to grow. She notes that the United Kingdom has banned the removal of deer antler velvet under its welfare-of-livestock regulations, unless the antlers have been damaged or most of the velvet has been shed.
Russian bodybuilders have claimed to benefit from deer antler velvet by increasing muscle and nerve strength in the late 1960’s. Earlier studies found similar results in laboratory animals and athletes given pantocrin, an extract of deer antler velvet. Several studies show a positive correlation between consistent use of deer antler velvet and cardiovascular health. Human subjects who used deer antler velvet were able to endure larger work loads and experienced a shorter recovery time between exercises.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor).